| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| BRISTOL MYERS SQUIBB CO | 1.9% | 426K | 0 | 426K | /s/ Amy Fallone | Amy Fallone / Corporate Secretary | |
| CELGENE CORPORATION | 1.9% | 426K | 0 | 426K | /s/ Amy Fallone | Amy Fallone / Vice President and Secretary |