| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 6.6% | 2,271,832 | 0 | 2,271,832 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 6% | 5,448,687 | 0 | 2,068,096 | Kristin Mariani | Head of North America Compliance, CCO |