| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 14% | 13,592,334 | 0 | 13,592,334 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 5.4% | 5,220,256 | 0 | 5,220,256 | Kristin Mariani | Head of North America Compliance, CCO |