| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 6.2% | 3.27M | 0 | 3.27M | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 5.3% | 2.8M | 0 | 2.8M | Kristin Mariani | Head of North America Compliance, CCO |