| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 6.2% | 3,266,260 | 0 | 3,266,260 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 5.3% | 2,802,530 | 0 | 2,802,530 | Kristin Mariani | Head of North America Compliance, CCO |