Operating Margin of Spero Therapeutics, Inc. from 31 Dec 2016 to 30 Sep 2025

Taxonomy & unit
ratio: %
Description
The operating margin measures the profit a company makes on a dollar of sales after accounting for the direct costs involved in earning those revenues.
Summary
Spero Therapeutics, Inc. quarterly and annual Operating Margin in % history and change rate from 31 Dec 2016 to 30 Sep 2025.
  • Spero Therapeutics, Inc. Operating Margin for the quarter ending 30 Sep 2025 was -115%, a 11033% decline year-over-year.
  • Spero Therapeutics, Inc. annual Operating Margin for 2024 was -153%, a 839% decline from 2023.
  • Spero Therapeutics, Inc. annual Operating Margin for 2023 was 21%.
  • Spero Therapeutics, Inc. annual Operating Margin for 2022 was -79%, a 84% increase from 2021.
Operating Margin, Quarterly (%)
Operating Margin, YoY Quarterly Change (%)
Operating Margin, Annual (%)
Operating Margin, YoY Annual Change (%)

Spero Therapeutics, Inc. Quarterly Operating Margin (%)

Period Value YoY Chg Change % Start Date End Date
Q3 2025 -115% -114% -11033% 01 Jul 2025 30 Sep 2025
Q2 2025 -118% -131% -1001% 01 Apr 2025 30 Jun 2025
Q1 2025 -166% -186% -949% 01 Jan 2025 31 Mar 2025
Q4 2024 -153% -174% -839% 01 Oct 2024 31 Dec 2024
Q3 2024 -1% +3% +74% 01 Jul 2024 30 Sep 2024
Q2 2024 13% +37% 01 Apr 2024 30 Jun 2024
Q1 2024 20% +69% 01 Jan 2024 31 Mar 2024
Q4 2023 21% +100% 01 Oct 2023 31 Dec 2023
Q3 2023 -4% +1081% +100% 01 Jul 2023 30 Sep 2023
Q2 2023 -24% +1053% +98% 01 Apr 2023 30 Jun 2023
Q1 2023 -49% +709% +94% 01 Jan 2023 31 Mar 2023
Q4 2022 -79% +403% +84% 01 Oct 2022 31 Dec 2022
Q3 2022 -1085% -630% -138% 01 Jul 2022 30 Sep 2022
Q2 2022 -1077% -664% -161% 01 Apr 2022 30 Jun 2022
Q1 2022 -758% -251% -50% 01 Jan 2022 31 Mar 2022
Q4 2021 -482% +366% +43% 01 Oct 2021 31 Dec 2021
Q3 2021 -455% +325% +42% 01 Jul 2021 30 Sep 2021
Q2 2021 -413% +315% +43% 01 Apr 2021 30 Jun 2021
Q1 2021 -507% +155% +23% 01 Jan 2021 31 Mar 2021
Q4 2020 -848% -500% -143% 01 Oct 2020 31 Dec 2020
Q3 2020 -780% -481% -161% 01 Jul 2020 30 Sep 2020
Q2 2020 -728% -389% -115% 01 Apr 2020 30 Jun 2020
Q1 2020 -662% -304% -85% 01 Jan 2020 31 Mar 2020
Q4 2019 -348% +731% +68% 01 Oct 2019 31 Dec 2019
Q3 2019 -299% +1101% +79% 01 Jul 2019 30 Sep 2019
Q2 2019 -338% +1058% +76% 01 Apr 2019 30 Jun 2019
Q1 2019 -358% +1144% +76% 01 Jan 2019 31 Mar 2019
Q4 2018 -1079% +1029% +49% 01 Oct 2018 31 Dec 2018
Q3 2018 -1400% 01 Jul 2018 30 Sep 2018
Q2 2018 -1396% 01 Apr 2018 30 Jun 2018
Q1 2018 -1502% 01 Jan 2018 31 Mar 2018
Q4 2017 -2109% 01 Oct 2017 31 Dec 2017

Spero Therapeutics, Inc. Annual Operating Margin (%)

Period Value YoY Chg Change % Start Date End Date
2024 -153% -174% -839% 01 Jan 2024 31 Dec 2024
2023 21% +100% 01 Jan 2023 31 Dec 2023
2022 -79% +403% +84% 01 Jan 2022 31 Dec 2022
2021 -482% +366% +43% 01 Jan 2021 31 Dec 2021
2020 -848% -500% -143% 01 Jan 2020 31 Dec 2020
2019 -348% +731% +68% 01 Jan 2019 31 Dec 2019
2018 -1079% +1029% +49% 01 Jan 2018 31 Dec 2018
2017 -2109% +7808% +79% 01 Jan 2017 31 Dec 2017
2016 -9917% 01 Jan 2016 31 Dec 2016
* An asterisk sign (*) next to the value indicates that the value is likely invalid.