Insider Transactions Reported by 24 Insiders of PROTHENA CORP PUBLIC LTD CO

Insiders trading volume in the past year

	Insiders	Shares	%	Avg Price	Total $
Buys	1	+100,000	1.6%	$12.79	+$1,279,040
Sells	1	-6,279,684	98%	$8.10	-$50,839,807
Net	0	-6,179,684	-97%		-$49,560,767

Name	Relationship	Holdings Value	Past Year Net Change	Change %	Report Date
EcoR1 Capital, LLC	10%+ Owner	$40,544,618	-$50,839,807	-56%	02 May 2025
WILLIAM P. SCULLY	10%+ Owner	$11,365,153	+$1,279,040	+13%	18 Dec 2024
Gene G. Kinney	President and CEO, Director	$1,159,698			28 Jul 2025
Brandon S. Smith	Chief Operating Officer	$986,700			28 Jul 2025
Tran Nguyen	Chief Strategy Officer and CFO	$737,785			28 Jul 2025
Wagner M. Zago	Chief Scientific Officer	$645,150			28 Jul 2025
Chad J. Swanson	Chief Development Officer	$645,150			28 Jul 2025
Michael Malecek	Chief Legal Officer	$607,200			28 Jul 2025
Karin L. Walker	Chief Accounting Officer	$189,750			28 Jul 2025
DANIEL G. WELCH	Director				14 May 2025
Carol D. Karp	Chief Regulatory Officer				05 Mar 2025
COLLIER RICHARD T	Director				14 May 2025
William H. Dunn Jr.	Director				14 May 2025
Hideki Garren	Chief Medical Officer				27 Feb 2024
Radhika Tripuraneni	Chief Development Officer				23 Feb 2022
Dennis J. Selkoe	Director				14 May 2025
David A. Ford	Chief People Officer				05 Mar 2025
CHRISTOPHER S. HENNEY	Director				14 Jul 2021
Lars Ekman	Director				14 May 2025
Helen Susan Kim	Director				14 May 2025
Shane Cooke	Director				14 May 2025
Paula K. Cobb	Director				14 May 2025
Sanjiv Patel	Director				18 May 2022
Karl Anders Olof Harfstrand	Director				17 May 2023

Insider	Symbol	Class	Transaction	%	Value $	* Price $	Shares	Shares Owned	Date	Ownership

* An asterisk sign (*) next to the price indicates that the price is likely invalid.