Tango Therapeutics, Inc.

Ownership Transactions Reported by 23 Insiders

	Insiders	Shares	%	Avg Price	Total $
Buys	1	+20K	0.2%	$3.70	+$74K
Sells	7	-9.97M	99.8%	$4.78	-$47.6M
Net	-6	-9.95M	-99.6%		-$47.6M

Name	Relationship	Holdings Value	Past Year Net Change	Change %	Report Date
Boxer Capital, LLC	Other*	$139M			Oct 13, 2023
Third Rock Ventures IV, L.P.	10%+ Owner	$111M	-$18.9M	-14.6%	Sep 25, 2025
BCTG Holdings, LLC	10%+ Owner	$58.6M			Aug 10, 2021
EcoR1 Capital, LLC	10%+ Owner	$31M	-$8.44M	-21.4%	Nov 6, 2024
Boxer Capital Management, LLC	Other*	$11.3M	-$20.1M	-64%	Nov 6, 2024
Barbara Weber	Chief Executive Officer, Director	$5.13M	-$57.7K	-1.11%	Feb 4, 2025
Third Rock Ventures VI, L.P.	Director	$1.63M			Aug 11, 2023
Alan Huang	Chief Scientific Officer	$1.41M			Mar 1, 2023
MVA Investors, LLC	Other*	$944K			Jun 28, 2024
Adam Crystal	President, Research & Development	$500K	-$43.9K	-8.06%	Feb 4, 2025
Daniella Beckman	Chief Financial Officer	$475K	-$25.3K	-5.05%	Feb 4, 2025
Braslyn Ltd.	10%+ Owner	$226K			Aug 10, 2021
Douglas Barry	General Counsel	$209K	-$16.4K	-7.27%	Feb 4, 2025
Mace Rothenberg	Director	$42.8K	+$74K		Jun 5, 2025
Reid M. Huber	Director	$42K			Jun 6, 2023
John B. Ketchum	Director	$23.9K			Jun 5, 2025
Malte Peters	Director	$20K			Jun 5, 2025
Alexis Borisy	Director	$20K			Jun 5, 2025
Lesley Ann Calhoun	Director	$14.3K			Jun 5, 2025
Kanishka Pothula	Director				Nov 6, 2023
Aaron Weitzman	Chief Medical Officer				Dec 1, 2022
Davis Aaron I.	Other*				Sep 3, 2024
Marc Rudoltz	Chief Medical Officer				Nov 1, 2021

Insider	Symbol	Class	Transaction	%	Value $	* Price $	Shares	Shares Owned	Date	Ownership

* An asterisk sign (*) next to the price indicates that the price is likely invalid.