Upstream Bio, Inc. financial data

Symbol
UPB on Nasdaq
Location
890 Winter Street, Suite 200, Waltham, MA
Fiscal year end
December 31
Latest financial report
10-Q - Q2 2025 - Aug 6, 2025

Key Ratios

Label TTM Value / Value Unit Change %
Current Ratio 3.75K %
Debt-to-equity 3.98 %
Return On Equity -35.9 % -214%
Return On Assets -26.3 %
Operating Margin -4.46K %

Shares

Label TTM Value / Value Unit Change %
Entity Common Stock, Shares Outstanding 53.9M shares
Common Stock, Shares, Outstanding 53.8M shares
Common Stock, Value, Issued 54K USD
Weighted Average Number of Shares Outstanding, Basic 53.8M shares +1687%
Weighted Average Number of Shares Outstanding, Diluted 53.8M shares +1687%

Income Statement

Label TTM Value / Value Unit Change %
Revenue from Contract with Customer, Excluding Assessed Tax 2.72M USD +83.7%
Research and Development Expense 101M USD +169%
General and Administrative Expense 23.4M USD +86.4%
Operating Income (Loss) -122M USD -153%
Nonoperating Income (Expense) 17.1M USD +53.1%
Income Tax Expense (Benefit) 0 USD
Net Income (Loss) Attributable to Parent -104M USD -158%
Earnings Per Share, Basic 4 USD/shares +88.6%
Earnings Per Share, Diluted 4 USD/shares +88.6%

Balance Sheet

Label TTM Value / Value Unit Change %
Cash and Cash Equivalents, at Carrying Value 45.5M USD -3.97%
Accounts Receivable, after Allowance for Credit Loss, Current 937K USD
Assets, Current 418M USD
Property, Plant and Equipment, Net 544K USD
Operating Lease, Right-of-Use Asset 1.51M USD
Goodwill 0 USD
Assets 421M USD
Accounts Payable, Current 2.55M USD
Employee-related Liabilities, Current 1.91M USD
Liabilities, Current 10.9M USD
Operating Lease, Liability, Noncurrent 849K USD
Liabilities 11.8M USD
Accumulated Other Comprehensive Income (Loss), Net of Tax 258K USD
Retained Earnings (Accumulated Deficit) -258M USD
Stockholders' Equity Attributable to Parent 409M USD
Liabilities and Equity 421M USD

Popular Metrics

Label TTM Value / Value Unit Change %
Net Cash Provided by (Used in) Operating Activities -41.2M USD -134%
Net Cash Provided by (Used in) Financing Activities -34K USD -100%
Net Cash Provided by (Used in) Investing Activities -213M USD -1640%
Common Stock, Shares Authorized 500M shares
Common Stock, Shares, Issued 53.8M shares
Common Stock, Par or Stated Value Per Share 0 USD/shares
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect -255M USD -4584%
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents 45.7M USD -3.56%
Deferred Tax Assets, Valuation Allowance 60.7M USD +52.8%
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent 0 pure
Deferred Tax Assets, Gross 61.2M USD +54%
Operating Lease, Liability 1.83M USD
Comprehensive Income (Loss), Net of Tax, Attributable to Parent -104M USD -172%
Lessee, Operating Lease, Liability, to be Paid 2.15M USD
Property, Plant and Equipment, Gross 785K USD
Operating Lease, Liability, Current 712K USD
Lessee, Operating Lease, Liability, to be Paid, Year Two 800K USD
Lessee, Operating Lease, Liability, to be Paid, Year One 700K USD
Operating Lease, Weighted Average Discount Rate, Percent 0.12 pure -25.5%
Lessee, Operating Lease, Liability, Undiscounted Excess Amount 311K USD
Lessee, Operating Lease, Liability, to be Paid, Year Three 800K USD
Deferred Tax Assets, Operating Loss Carryforwards 11M USD +57.4%
Preferred Stock, Shares Issued 0 shares
Preferred Stock, Shares Authorized 10M shares
Unrecognized Tax Benefits 0 USD
Additional Paid in Capital 666M USD
Preferred Stock, Shares Outstanding 0 shares
Depreciation, Depletion and Amortization 43K USD +231%
Deferred Tax Assets, Net of Valuation Allowance 488K USD +3967%
Share-based Payment Arrangement, Expense 9.18M USD +83.9%
Preferred Stock, Par or Stated Value Per Share 0 USD/shares