Upstream Bio, Inc. financial data

Symbol
UPB on Nasdaq
Location
Waltham, MA
Fiscal year end
31 December
Latest financial report
10-Q - Q3 2025 - 05 Nov 2025

Key Ratios

Label TTM Value / Value Unit Change %
Current Ratio 4034% %
Debt-to-equity 3% %
Return On Equity -29% % -176%
Return On Assets -28% %
Operating Margin -5020% %

Shares

Label TTM Value / Value Unit Change %
Entity Common Stock, Shares Outstanding 54,038,591 shares 0.82%
Common Stock, Shares, Outstanding 53,999,522 shares 1685%
Common Stock, Value, Issued $56,000 USD 1767%
Weighted Average Number of Shares Outstanding, Basic 53,930,946 shares 1684%
Weighted Average Number of Shares Outstanding, Diluted 53,930,946 shares 1684%

Income Statement

Label TTM Value / Value Unit Change %
Revenue from Contract with Customer, Excluding Assessed Tax $2,799,000 USD 13%
Research and Development Expense $118,410,000 USD 114%
General and Administrative Expense $24,901,000 USD 36%
Operating Income (Loss) $140,512,000 USD -100%
Nonoperating Income (Expense) $18,286,000 USD 41%
Net Income (Loss) Attributable to Parent $122,226,000 USD -129%
Earnings Per Share, Basic 10 USD/shares 91%
Earnings Per Share, Diluted 10 USD/shares 91%

Balance Sheet

Label TTM Value / Value Unit Change %
Cash and Cash Equivalents, at Carrying Value $72,164,000 USD 119%
Accounts Receivable, after Allowance for Credit Loss, Current $683,000 USD 13%
Assets, Current $389,017,000 USD 71%
Property, Plant and Equipment, Net $616,000 USD 6.6%
Operating Lease, Right-of-Use Asset $1,368,000 USD -29%
Assets $391,195,000 USD 68%
Accounts Payable, Current $3,952,000 USD -19%
Employee-related Liabilities, Current $3,037,000 USD 52%
Liabilities, Current $11,908,000 USD 9.5%
Operating Lease, Liability, Noncurrent $703,000 USD -44%
Liabilities $12,611,000 USD 3.9%
Accumulated Other Comprehensive Income (Loss), Net of Tax $493,000 USD 40%
Retained Earnings (Accumulated Deficit) $291,764,000 USD -72%
Stockholders' Equity Attributable to Parent $378,584,000 USD
Liabilities and Equity $391,195,000 USD 68%

Popular Metrics

Label TTM Value / Value Unit Change %
Common Stock, Shares Authorized 500,000,000 shares 1129%
Common Stock, Shares, Issued 53,999,522 shares 1685%
Common Stock, Par or Stated Value Per Share 0 USD/shares 0%
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents $72,358,000 USD 118%
Comprehensive Income (Loss), Net of Tax, Attributable to Parent $122,084,000 USD -115%
Property, Plant and Equipment, Gross $903,000 USD 32%
Operating Lease, Liability, Current $716,000 USD 5.6%
Lessee, Operating Lease, Liability, to be Paid, Year Two $800,000 USD 0%
Lessee, Operating Lease, Liability, to be Paid, Year One $700,000 USD 0%
Lessee, Operating Lease, Liability, to be Paid, Year Three $800,000 USD 0%
Preferred Stock, Shares Issued 0 shares
Preferred Stock, Shares Authorized 10,000,000 shares
Additional Paid in Capital $669,799,000 USD 7449%
Preferred Stock, Shares Outstanding 0 shares
Share-based Payment Arrangement, Expense $9,912,000 USD 39%
Preferred Stock, Par or Stated Value Per Share 0 USD/shares