Baker Bros. Advisors Lp - Insider Trading & Ownership

Location
860 Washington Street, 3 Rd Floor, New York, NY
Summary
The estimated value of insider holdings of Baker Bros. Advisors Lp is at least $7.66B dollars as of November 24, 2025. Baker Bros. Advisors Lp is the Director, 10%+ Owner of INCYTE CORP and owns shares of INCYTE CORP (INCY) stock worth about $2.38B. Baker Bros. Advisors Lp is the Director of BeiGene, Ltd. and owns shares of BeiGene, Ltd. (ONC) stock worth about $2.14B. Baker Bros. Advisors Lp is the Director of MADRIGAL PHARMACEUTICALS, INC. and owns shares of MADRIGAL PHARMACEUTICALS, INC. (MDGL) stock worth about $764M. Baker Bros. Advisors Lp is the Director of Kymera Therapeutics, Inc. and owns shares of Kymera Therapeutics, Inc. (KYMR) stock worth about $719M. Baker Bros. Advisors Lp is the Director, 10%+ Owner of ACADIA PHARMACEUTICALS INC and owns shares of ACADIA PHARMACEUTICALS INC (ACAD) stock worth about $688M. Baker Bros. Advisors Lp is the Director, 10%+ Owner of BICYCLE THERAPEUTICS PLC and owns shares of BICYCLE THERAPEUTICS PLC (BCYC) stock worth about $536M. Baker Bros. Advisors Lp is the Director, 10%+ Owner of Replimune Group, Inc. and owns shares of Replimune Group, Inc. (REPL) stock worth about $126M. Baker Bros. Advisors Lp is the 10%+ Owner of Celcuity Inc. and owns shares of Celcuity Inc. (CELC) stock worth about $77.9M. Baker Bros. Advisors Lp is the Director of Kiniksa Pharmaceuticals International, plc and owns shares of Kiniksa Pharmaceuticals International, plc (KNSA) stock worth about $70.5M. Baker Bros. Advisors Lp is the Director of Immunocore Holdings plc and owns shares of Immunocore Holdings plc (IMCR) stock worth about $63.4M. Baker Bros. Advisors Lp is the Director of Denali Therapeutics Inc. and owns shares of Denali Therapeutics Inc. (DNLI) stock worth about $56.2M. Baker Bros. Advisors Lp is the 10%+ Owner of Entrada Therapeutics, Inc. and owns shares of Entrada Therapeutics, Inc. (TRDA) stock worth about $42.6M. Baker Bros. Advisors Lp is the Former 10% Owner of Atreca, Inc. and owns shares of Atreca, Inc. stock worth about $1.2M. Baker Bros. Advisors Lp is the Former 10% owner of KALA BIO, Inc. and owns shares of KALA BIO, Inc. (KALA) stock worth about $588K. Baker Bros. Advisors Lp is the Director, Former 10% Owner of Neurogene Inc. and owns shares of Neurogene Inc. (NGNE) stock worth about $287K.
Signature
By: Baker Bros. Advisors (GP) LLC, Name: Scott L. Lessing, Title: President /s/ Scott L. Lessing
All Insider Reports
All Insider Reports

Ownership of Baker Bros. Advisors Lp

Symbol Company Relationship Holdings Value Past Year Net Change Change % Report Period
INCY INCYTE CORP Director, 10%+ Owner $2.38B Sep 30, 2025
ONC, BEIGF BeiGene, Ltd. Director $2.14B -$385M -15.3% May 21, 2025
MDGL MADRIGAL PHARMACEUTICALS, INC. Director $764M +$61.9M +8.82% Aug 18, 2025
KYMR Kymera Therapeutics, Inc. Director $719M +$57.7M +8.72% Jun 30, 2025
ACAD ACADIA PHARMACEUTICALS INC Director, 10%+ Owner $688M May 29, 2025
BCYC BICYCLE THERAPEUTICS PLC Director, 10%+ Owner $536M +$21.2M +4.13% Jan 2, 2025
REPL Replimune Group, Inc. Director, 10%+ Owner $126M Mar 5, 2025
CELC Celcuity Inc. 10%+ Owner $77.9M Sep 8, 2025
KNSA Kiniksa Pharmaceuticals International, plc Director $70.5M Jun 3, 2025
IMCR Immunocore Holdings plc Director $63.4M +$24M +60.9% May 15, 2025
DNLI Denali Therapeutics Inc. Director $56.2M Jun 3, 2025
TRDA Entrada Therapeutics, Inc. 10%+ Owner $42.6M +$1.61M +3.94% Nov 20, 2025
BCEL Atreca, Inc. Former 10% Owner $1.2M Oct 19, 2023
KALA KALA BIO, Inc. Former 10% owner $588K +$943K Sep 30, 2025
NGNE Neurogene Inc. Director, Former 10% Owner $287K Dec 18, 2023
IGMS IGM Biosciences, Inc. Former 10% owner and director $0 Aug 14, 2025
SYRE Spyre Therapeutics, Inc. Director Jun 8, 2021
BLCM BELLICUM PHARMACEUTICALS, INC 10%+ Owner Nov 22, 2023
DBVT, DBVTF DBV Technologies S.A. Director, 10%+ Owner Mar 27, 2025
KOD Kodiak Sciences Inc. Director, 10%+ Owner Jun 30, 2025
PRLD Prelude Therapeutics Inc Director, 10%+ Owner Jun 12, 2025
SGEN Seagen Inc. Director, Former 10% Owner Dec 14, 2023
SERA SERA PROGNOSTICS, INC. 10%+ Owner Feb 12, 2025
TLIS Talis Biomedical Corp Director, 10%+ Owner Jun 9, 2023
TCRX TScan Therapeutics, Inc. Director Jun 30, 2025
VTVT vTv Therapeutics Inc. Director Sep 3, 2025

Insider Transactions Reported by Baker Bros. Advisors Lp:

Sym Company Class Transaction % Value $ * Price $ Shares Shares After Date Ownership
* An asterisk sign (*) next to the price indicates that the price is likely invalid.