| Name | Relationship | Address | Signature | Signature date | CIK | 
|---|---|---|---|---|---|
| RASTETTER WILLIAM H | Director | 6027 EDGEWOOD BEND COURT, SAN DIEGO | /s/ Darin Lippoldt, Attorney-in-Fact | 2025-05-22 | 0001205903 | 
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes | 
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | NBIX | Common Stock | Options Exercise | $0 | +2.87K | +7.65% | $0.00 | 40.4K | May 22, 2025 | Direct | F1 | 
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes | 
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | NBIX | Restricted Stock Unit | Award | $0 | +3.32K | $0.00 | 3.32K | May 21, 2025 | Common Stock | 3.32K | $0.00 | Direct | F2, F3 | |
| transaction | NBIX | Restricted Stock Unit | Options Exercise | $0 | -2.87K | -100% | $0.00 | 0 | May 22, 2025 | Common Stock | 2.87K | $0.00 | Direct | F2, F4 | 
| Id | Content | 
|---|---|
| F1 | 40,360 of the reported shares are held by the Rastetter Family Trust established September 2, 2010, of which the Reporting Person has voting and investment power. | 
| F2 | Each Restricted Stock Unit ("RSU") represents the right to receive one share of the Issuer's common stock upon vesting. | 
| F3 | The RSUs will vest in full on May 21, 2026. | 
| F4 | This RSU award was granted to the Reporting Person on May 22, 2024 and is fully vested. |