FRANK E. THOMAS - 01 Mar 2023 Form 4 Insider Report for Orchard Therapeutics plc

Role: Title: President & Chief Operating Officer
Signature: /s/ Frank E. Thomas
Issuer symbol: N/A
Transactions as of: 01 Mar 2023
Net transactions value: $0
Form type: 4
Filing time: 03 Mar 2023, 17:00:29 UTC
Previous filing: 13 Feb 2023
Next filing: 14 Mar 2023
SEC: View on sec.gov

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	ORTX	Stock Option (Right to Buy)	Award	$0	+405,600		$0.000000	405,600	01 Mar 2023	Ordinary Shares	405,600	$0.4636	Direct	F1, F2
transaction	ORTX	Stock Option (Right to Buy)	Award	$0	+179,400		$0.000000	179,400	01 Mar 2023	Ordinary Shares	179,400	$0.5795	Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The shares subject to this option shall vest and become exercisable in forty-eight (48) equal monthly installments, with the first installment vesting on April 1, 2023.
F2	The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents one Ordinary Share.

Remarks:

Title: President & Chief Operating Officer