FRANK E. THOMAS - 10 Mar 2023 Form 4 Insider Report for Orchard Therapeutics plc

Role: Title: President & Chief Operating Officer
Signature: /s/ Frank Thomas
Issuer symbol: N/A
Transactions as of: 10 Mar 2023
Net transactions value: +$9,182
Form type: 4
Filing time: 14 Mar 2023, 08:30:50 UTC
Previous filing: 03 Mar 2023
Next filing: 11 May 2023
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	ORTX	Ordinary Shares	Options Exercise	$9,182	+20,000	+28%	$0.4591	92,081	10 Mar 2023	Direct	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	ORTX	Stock Option (Right to Buy)	Options Exercise	$0	-20,000	-5.6%	$0.000000	335,000	10 Mar 2023	Ordinary Shares	20,000	$0.4591	Direct	F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents ten Ordinary Shares.
F2	The shares subject to this option vest and become exercisable in twenty-four (24) equal monthly installments, with the first installment vested on March 1, 2022.

Remarks:

Title: President & Chief Operating Officer