Opaleye Management Inc. - Jul 31, 2025 Form 4 Insider Report for CODEXIS, INC. (CDXS)

Role
10%+ Owner
Signature
Opaleye Management Inc., By: /s/ James Silverman, President
Stock symbol
CDXS
Transactions as of
Jul 31, 2025
Transactions value $
$227,921
Form type
4
Date filed
8/4/2025, 04:38 PM
Previous filing
Jul 31, 2025
Next filing
Oct 9, 2025
SEC
View on sec.gov

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Opaleye Management Inc. 10%+ Owner ONE BOSTON PLACE, 26TH FLOOR, BOSTON Opaleye Management Inc., By: /s/ James Silverman, President 2025-08-04 0001595855

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction CDXS Common Stock, par value $0.001 per share Purchase $226K +84.2K +0.68% $2.68 12.5M Jul 31, 2025 By Opaleye, L.P. F1, F3
transaction CDXS Common Stock, par value $0.001 per share Purchase $2.21K +780 +0.01% $2.84 12.5M Aug 4, 2025 By Opaleye, L.P. F1, F3
holding CDXS Common Stock, par value $0.001 per share 250K Jul 31, 2025 By Managed Account F2, F3
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.
F2 Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.
F3 Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.