Fmr Llc - Jun 30, 2025 SCHEDULE 13G/A Report for UPSTREAM BIO INC COMMON STOCK (UPB)

Filing Manager
FMR LLC
Reporting Manager
FMR LLC
Symbol
UPB
Shares outstanding
53.6M shares
Disclosed Ownership
7.94M shares
Ownership
14.8%
Form type
SCHEDULE 13G/A
Date filed
8/6/2025, 12:19 PM
Date of event
Jun 30, 2025
Previous filing
Feb 12, 2025

Reporting Managers (2)

Name Ownership Shares Owned sole voting power shared voting power Signature Title CIK
FMR LLC 14.8% 7.94M 7.94M 0 Richard Bourgelas Duly authorized under Power of Attorney effective as of May 23, 2023, by and on behalf of FMR LLC and its direct and indirect subsidiaries*
Abigail P. Johnson 14.8% 7.94M 0 0 Richard Bourgelas Duly authorized under Power of Attorney effective as of May 23, 2023, by and on behalf of Abigail P. Johnson*