| Avidity Partners Management LP | 
            5.9% | 
            5.62M | 
            0 | 
            5.62M | 
            By: Avidity Partners Management (GP) LLC, its general partner, By: /s/ Michael Gregory | 
            Michael Gregory/Managing Member | 
             | 
          
          
            | Avidity Partners Management (GP) LLC | 
            5.9% | 
            5.62M | 
            0 | 
            5.62M | 
            /s/ Michael Gregory | 
            Michael Gregory/Managing Member | 
             | 
          
          
            | Avidity Capital Partners Fund (GP) LP | 
            5.9% | 
            5.62M | 
            0 | 
            5.62M | 
            By: Avidity Capital Partners (GP) LLC, its general partner, By: /s/ Michael Gregory | 
            Michael Gregory/Managing Member | 
             | 
          
          
            | Avidity Capital Partners (GP) LLC | 
            5.9% | 
            5.62M | 
            0 | 
            5.62M | 
            /s/ Michael Gregory | 
            Michael Gregory/Managing Member | 
             | 
          
          
            | Avidity Private Master Fund I LP | 
            4.9% | 
            4.7M | 
            0 | 
            4.7M | 
            By: Avidity Capital Partners Fund (GP) LP, its general partner, By: Avidity Capital Partners (GP) LLC, its general partner, By: /s/ Michael Gregory | 
            Michael Gregory/Managing Member | 
             | 
          
          
            | Michael Gregory | 
            5.9% | 
            5.62M | 
            0 | 
            5.62M | 
            /s/ Michael Gregory | 
            Michael Gregory | 
             |