| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| Redmile Group, LLC | 5.6% | 4.15M | 0 | 4.15M | /s/ Jeremy C. Green | Managing Member | |
| Jeremy C. Green | 5.6% | 4.15M | 0 | 4.15M | /s/ Jeremy C. Green | Jeremy C. Green | |
| Redmile Biopharma Investments III, L.P. | 4.6% | 3.47M | 0 | 3.47M | /s/ Jeremy C. Green | Managing Member of Redmile Biopharma Investments III (GP), LLC, general partner of Redmile Biopharma Investments III, L.P. |