| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 10% | 12,104,911 | 0 | 12,104,911 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 5.3% | 6,201,300 | 0 | 6,201,300 | Kristin Mariani | Head of North America Compliance, CCO |