| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 10% | 15,917,259 | 0 | 15,917,259 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 9.3% | 14,384,501 | 0 | 14,384,501 | Kristin Mariani | Head of North America Compliance, CCO |