| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 11% | 2,300,231 | 0 | 2,300,231 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 5.5% | 1,122,115 | 0 | 1,122,115 | Kristin Mariani | Head of North America Compliance, CCO |