| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 12% | 2,533,405 | 0 | 2,533,405 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 5.8% | 1,186,586 | 0 | 1,186,586 | Kristin Mariani | Head of North America Compliance, CCO |