| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 11% | 4,102,620 | 0 | 4,102,620 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 9.1% | 3,512,932 | 0 | 3,512,932 | Kristin Mariani | Head of North America Compliance, CCO |