| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 11% | 4,231,331 | 0 | 4,231,331 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 9.3% | 3,579,068 | 0 | 3,579,068 | Kristin Mariani | Head of North America Compliance, CCO |