| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 14% | 4,165,767 | 0 | 4,165,767 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 12% | 3,575,276 | 0 | 3,575,276 | Kristin Mariani | Head of North America Compliance, CCO |