JANUS HENDERSON GROUP PLC - 30 Sep 2025 SCHEDULE 13G Report for XENON PHARMACEUTICALS INC. Common Stock (XENE)

Filing Manager: JANUS HENDERSON GROUP PLC
Reporting Manager: JANUS HENDERSON GROUP PLC
Security: XENON PHARMACEUTICALS INC. Common Stock
Symbol: XENE
Shares outstanding: 77,331,078 shares
Disclosed Ownership: 3,943,885 shares
Ownership: 5.1%
Form type: SCHEDULE 13G
Filing time: 14 Nov 2025, 10:29:36 UTC
Date of event: 30 Sep 2025
SEC: View on sec.gov

Reporting Managers (1)

Name	Ownership	Shares Owned	sole voting power	shared voting power	Signature	Title	CIK
JANUS HENDERSON GROUP PLC	5.1%	3,943,885	0	3,943,885	Kristin Mariani	Head of North America Compliance, CCO