| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 10.2% | 16.3M | 0 | 16.3M | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 8.7% | 13.8M | 0 | 13.8M | Kristin Mariani | Head of North America Compliance, CCO |