Janus Henderson Group Plc - Sep 30, 2025 SCHEDULE 13G/A Report for MADRIGAL PHARMACEUTICALS, INC. Common Stock (MDGL)

Filing Manager: JANUS HENDERSON GROUP PLC
Reporting Manager: JANUS HENDERSON GROUP PLC
Security: MADRIGAL PHARMACEUTICALS, INC. Common Stock
Symbol: MDGL
Shares outstanding: 22.2M shares
Disclosed Ownership: 1.84M shares
Ownership: 8.3%
Form type: SCHEDULE 13G/A
Date filed: 11/14/2025, 12:06 PM
Date of event: Sep 30, 2025
Previous filing: Aug 14, 2025
SEC: View on sec.gov

Reporting Managers (1)

Name	Ownership	Shares Owned	sole voting power	shared voting power	Signature	Title	CIK
JANUS HENDERSON GROUP PLC	8.3%	1.84M	0	1.84M	Kristin Mariani	Head of North America Compliance, CCO