| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 11.3% | 6.11M | 0 | 6.11M | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 7.6% | 4.08M | 0 | 4.08M | Kristin Mariani | Head of North America Compliance, CCO |