| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 10% | 3,382,836 | 0 | 3,382,836 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 6.1% | 2,067,781 | 0 | 2,067,781 | Kristin Mariani | Head of North America Compliance, CCO |