Perceptive Advisors Llc

Insider Reports History

Location
51 Astor Place, 10 Th Floor, New York, NY
Signature
/s/ Joseph Edelman - for Perceptive Life Sciences Master Fund Ltd., By: Perceptive Advisors LLC, its investment manager, By: Joseph Edelman, its managing member
All insider transactions
Transactions in reports broken out by “transaction date” reported in original SEC filing, see here for transactions aggregated across transaction date

Holdings reported by Perceptive Advisors Llc:

Stock Role Class Num Shares Value Price $ Report Date Ownership
Crinetics Pharmaceuticals, Inc. 10%+ Owner Common Stock 5.32M $200M $37.65 Apr 18, 2022 Indirect
VBI Vaccines Inc/BC 10%+ Owner Common Stock 41.4M $114M $2.75 Apr 6, 2023 Indirect
SOLENO THERAPEUTICS INC 10%+ Owner Common Stock 3.07M $112M $36.49 Sep 28, 2023 Indirect
ALBIREO PHARMA, INC. 10%+ Owner Common Stock 1.94M $85M $43.80 Oct 13, 2022 Indirect
ADMA BIOLOGICS, INC. 10%+ Owner Common Stock 13.3M $59.9M $4.52 Sep 30, 2021 Indirect
Astria Therapeutics, Inc. Director Common Stock 4.87M $58.9M $12.09 Feb 1, 2024 Indirect
Verrica Pharmaceuticals Inc. 10%+ Owner Common Stock 7.1M $51.4M $7.24 Dec 29, 2023 Indirect
MeiraGTx Holdings plc Director, 10%+ Owner Ordinary Shares 12.5M $50.1M $4.00 Aug 12, 2024 Indirect
Solid Biosciences Inc. Director, 10%+ Owner Common Stock 11.8M $47.7M $4.03 Feb 19, 2025 Indirect
Aldeyra Therapeutics, Inc. 10%+ Owner Common Stock 5.88M $27.8M $4.74 Apr 3, 2025 Indirect
AGILE THERAPEUTICS INC 10%+ Owner Common Stock 21.7M $18.4M $0.85 Oct 13, 2021 Indirect
Orchestra BioMed Holdings, Inc. 10%+ Owner Common Stock 5.29M $14.6M $2.75 Aug 1, 2025 Indirect
Athira Pharma, Inc. Director, 10%+ Owner Common Stock 5.4M $12.9M $2.38 Dec 29, 2023 Indirect
VYNE Therapeutics Inc. 10%+ Owner Common Stock 4.94M $11.3M $2.28 Aug 16, 2021 Indirect
LEAP THERAPEUTICS, INC. 10%+ Owner Warrants (right to buy) 3.51M $10M $2.85 Sep 24, 2021 Indirect
Astria Therapeutics, Inc. Director Pre-funded Warrants (right to buy) 921K $6M $6.51 Oct 16, 2023 Indirect
CARGO Therapeutics, Inc. Former 10% Owner Common Stock 333K $5M $15.00 Nov 14, 2023 Indirect
SOLENO THERAPEUTICS INC 10%+ Owner Pre-funded warrants (right to buy) 250K $5M $19.99 Sep 28, 2023 Indirect
Acrivon Therapeutics, Inc. 10%+ Owner Common Stock 3.1M $4.16M $1.34 May 1, 2025 Indirect
Orchestra BioMed Holdings, Inc. 10%+ Owner Pre-funded Warrants (right to buy) 1.5M $4.12M $2.75 Aug 1, 2025 Indirect
Adagio Medical Holdings, Inc. Director, 10%+ Owner Pre-Funded Warrant (right to buy) 2.19M $3.51M $1.60 Oct 20, 2025 Indirect
Rain Therapeutics Inc. 10%+ Owner Common Stock 2.49M $3.01M $1.21 Oct 12, 2021 Indirect
IsoPlexis Corp 10%+ Owner Common Stock 3.55M $2.58M $0.73 Oct 12, 2021 By Perceptive Life Sciences Master Fund, Ltd.
Astria Therapeutics, Inc. Director Common Warrants (right to buy) 345K $2.25M $6.51 Oct 16, 2023 Indirect
Landos Biopharma, Inc. 10%+ Owner Pre-funded Warrant 3.64M $1.96M $0.54 Jan 10, 2023 Indirect
CHEMBIO DIAGNOSTICS, INC. 10%+ Owner Common Stock 3.67M $1.65M $0.45 Apr 4, 2023 Indirect
Quotient Ltd 10%+ Owner Ordinary Shares, nil par value 7.95M $636K $0.08 Oct 31, 2022 Indirect
IsoPlexis Corp 10%+ Owner Common Stock 336K $244K $0.73 Oct 12, 2021 By Perceptive Credit Holdings III, LP
IsoPlexis Corp 10%+ Owner Common Stock 205K $149K $0.73 Oct 12, 2021 By PCOF EQ AIV III, LP
LianBio Director, 10%+ Owner Ordinary Shares 17.1K $81.3K $4.76 Feb 15, 2024 Indirect
Lyra Therapeutics, Inc. 10%+ Owner Common Stock 14K $54.7K $3.90 Nov 13, 2025 Indirect
Cerevel Therapeutics Holdings, Inc. Director Common Stock 0 $0 $41.54 Feb 20, 2024 Indirect
Adagio Medical Holdings, Inc. Director, 10%+ Owner Common Stock 9.68M Jan 22, 2025 Direct
LianBio Director, 10%+ Owner American Depository Shares 3.73M Feb 15, 2024 Indirect
AGILE THERAPEUTICS INC 10%+ Owner Warrants (right to buy) 2.69M Oct 13, 2021 Indirect
SOLENO THERAPEUTICS INC 10%+ Owner 210859 2.03M May 26, 2023 Indirect
Adagio Medical Holdings, Inc. Director, 10%+ Owner Tranche A Warrant ("Common Warrant" right to buy) 1.34M Oct 20, 2025 Indirect
Adagio Medical Holdings, Inc. Director, 10%+ Owner Tranche B Warrant ("Common Warrant" right to buy) 1.34M Oct 20, 2025 Indirect
Adagio Medical Holdings, Inc. Director, 10%+ Owner Tranche C Warrant ("Common Warrant" right to buy) 1.34M Oct 20, 2025 Indirect
Adagio Medical Holdings, Inc. Director, 10%+ Owner Common Stock 201K Jan 22, 2025 Indirect
Solid Biosciences Inc. Director, 10%+ Owner Director Stock Option (Right to Buy) 77.5K Jun 12, 2025 Indirect
MeiraGTx Holdings plc Director, 10%+ Owner Restricted Share Units 45K Jun 12, 2025 Indirect
Nautilus Biotechnology, Inc. Director, 10%+ Owner Stock Option (Right to Buy) 45K Jun 14, 2024 Indirect
CARGO Therapeutics, Inc. Former 10% Owner Series A-1 Convertible Preferred Stock 0 Nov 14, 2023 Indirect
IsoPlexis Corp 10%+ Owner Series D Redeemable Convertible Preferred Stock 0 Oct 12, 2021 By PCOF EQ AIV III, LP
IsoPlexis Corp 10%+ Owner Series D Redeemable Convertible Preferred Stock 0 Oct 12, 2021 By Perceptive Credit Holdings III, LP
IsoPlexis Corp 10%+ Owner Series D Redeemable Convertible Preferred Stock 0 Oct 12, 2021 By Perceptive Life Sciences Master Fund, Ltd.
LianBio Director, 10%+ Owner Stock Option (Right to Buy) 0 Feb 15, 2024 Indirect

Insider Reports Filed by Perceptive Advisors Llc

Symbol Company Period Transactions Value $ Form Type Date Filed Role
LYRA Lyra Therapeutics, Inc. Nov 11, 2025 6 -$183K 4 Nov 13, 2025 10%+ Owner
LYRA Lyra Therapeutics, Inc. Nov 6, 2025 6 -$344K 4 Nov 10, 2025 10%+ Owner
ADGM Adagio Medical Holdings, Inc. Oct 20, 2025 4 $4.25M 4 Oct 22, 2025 Director, 10%+ Owner
OBIO Orchestra BioMed Holdings, Inc. Aug 1, 2025 2 $6.05M 4 Aug 5, 2025 10%+ Owner
MGTX MeiraGTx Holdings plc Jun 12, 2025 1 $0 4 Jun 16, 2025 Director, 10%+ Owner
SLDB Solid Biosciences Inc. Jun 12, 2025 1 $0 4 Jun 13, 2025 Director, 10%+ Owner
ACRV Acrivon Therapeutics, Inc. Apr 30, 2025 2 -$1.02M 4 May 1, 2025 10%+ Owner
ACRV Acrivon Therapeutics, Inc. Apr 25, 2025 3 -$2.74M 4 Apr 29, 2025 10%+ Owner
ALDX Aldeyra Therapeutics, Inc. Apr 3, 2025 1 -$4.83M 4 Apr 7, 2025 10%+ Owner
SLDB Solid Biosciences Inc. Feb 19, 2025 1 $20.2M 4 Feb 21, 2025 Director, 10%+ Owner
ADGM Adagio Medical Holdings, Inc. Jan 22, 2025 1 $0 4 Feb 14, 2025 Director, 10%+ Owner
MGTX MeiraGTx Holdings plc Aug 12, 2024 1 $5M 4 Aug 14, 2024 Director, 10%+ Owner
ADGM Aja Holdco, Inc. Jul 31, 2024 0 $0 3 Aug 1, 2024 Director, 10%+ Owner
OBIO Orchestra BioMed Holdings, Inc. Jul 11, 2024 0 $0 3 Jul 17, 2024 10%+ Owner
VAPO VAPOTHERM INC Jun 17, 2024 0 $0 3 Jun 27, 2024 10%+ Owner
NAUT Nautilus Biotechnology, Inc. Jun 14, 2024 1 $0 4 Jun 17, 2024 Director, 10%+ Owner
SLDB Solid Biosciences Inc. Jun 11, 2024 1 $0 4 Nov 19, 2024 Director, 10%+ Owner
MGTX MeiraGTx Holdings plc Jun 6, 2024 1 $0 4 Jun 7, 2024 Director, 10%+ Owner
ACRV Acrivon Therapeutics, Inc. Apr 11, 2024 1 $20M 4 Apr 15, 2024 10%+ Owner
ALDX Aldeyra Therapeutics, Inc. Apr 4, 2024 2 $834K 4 Apr 8, 2024 10%+ Owner
ALDX Aldeyra Therapeutics, Inc. Apr 1, 2024 3 $1.93M 4 Apr 3, 2024 10%+ Owner
CERE Cerevel Therapeutics Holdings, Inc. Feb 20, 2024 1 $0 4 Feb 21, 2024 Director
LIAN LianBio Feb 15, 2024 6 -$3 4 Feb 20, 2024 Director, 10%+ Owner
ATXS Astria Therapeutics, Inc. Feb 1, 2024 1 $30M 4 Feb 5, 2024 Director
SLDB Solid Biosciences Inc. Jan 11, 2024 1 $18.9M 4 Jan 12, 2024 Director, 10%+ Owner
VRCA Verrica Pharmaceuticals Inc. Dec 27, 2023 3 $2.31M 4 Dec 29, 2023 10%+ Owner
ATHA Athira Pharma, Inc. Dec 27, 2023 3 $1.46M 4 Dec 29, 2023 Director, 10%+ Owner
VRCA Verrica Pharmaceuticals Inc. Dec 21, 2023 3 $3.26M 4 Dec 26, 2023 10%+ Owner
ATXS Astria Therapeutics, Inc. Dec 21, 2023 1 $4.59M 4 Dec 22, 2023 Director
VRCA Verrica Pharmaceuticals Inc. Dec 15, 2023 3 $6.94M 4 Dec 19, 2023 10%+ Owner
CRGX CARGO Therapeutics, Inc. Nov 14, 2023 4 $10M 4 Nov 14, 2023 Former 10% Owner
CRGX CARGO Therapeutics, Inc. Nov 9, 2023 0 $0 3 Nov 9, 2023 10%+ Owner
ALDX Aldeyra Therapeutics, Inc. Oct 16, 2023 2 -$4.45M 4 Oct 18, 2023 10%+ Owner
ATXS Astria Therapeutics, Inc. Oct 16, 2023 6 $26M 4 Oct 18, 2023 Director
CERE Cerevel Therapeutics Holdings, Inc. Oct 16, 2023 1 $20M 4 Oct 17, 2023 Director
SLNO SOLENO THERAPEUTICS INC Sep 26, 2023 16 $20.1M 4 Sep 28, 2023 10%+ Owner
LIAN LianBio Jun 21, 2023 2 $0 4 Jun 23, 2023 Director, 10%+ Owner
NAUT Nautilus Biotechnology, Inc. Jun 15, 2023 1 $0 4 Jun 20, 2023 Director
MGTX MeiraGTx Holdings plc Jun 8, 2023 2 $0 4 Jun 12, 2023 Director, 10%+ Owner
SLDB Solid Biosciences Inc. Jun 6, 2023 1 $0 4 Jun 8, 2023 Director, 10%+ Owner
SLNO SOLENO THERAPEUTICS INC Jun 2, 2023 3 $854K 4 Jun 6, 2023 10%+ Owner
LYRA Lyra Therapeutics, Inc. May 31, 2023 2 $9M 4 Jun 2, 2023 Director, 10%+ Owner
SLNO SOLENO THERAPEUTICS INC May 30, 2023 3 $188K 4 Jun 1, 2023 10%+ Owner
SLNO SOLENO THERAPEUTICS INC May 24, 2023 3 $450K 4 May 26, 2023 10%+ Owner
SLNO SOLENO THERAPEUTICS INC May 19, 2023 3 $406K 4 May 23, 2023 10%+ Owner
SLNO SOLENO THERAPEUTICS INC May 11, 2023 0 $0 3 May 18, 2023 10%+ Owner
MGTX MeiraGTx Holdings plc May 5, 2023 1 $25M 4 May 15, 2023 Director, 10%+ Owner
CEMI CHEMBIO DIAGNOSTICS, INC. Apr 4, 2023 0 $0 3 Apr 6, 2023 10%+ Owner
VBIV VBI Vaccines Inc/BC Apr 4, 2023 3 -$1.48M 4 Apr 6, 2023 10%+ Owner
LABP Landos Biopharma, Inc. Jan 10, 2023 2 $16.7M 4 Jan 11, 2023 10%+ Owner
ATXS Astria Therapeutics, Inc. Dec 19, 2022 1 $10M 4 Dec 21, 2022 Director
SLDB Solid Biosciences Inc. Dec 13, 2022 1 $0 4 Dec 15, 2022 Director, 10%+ Owner
SLDB Solid Biosciences Inc. Dec 2, 2022 3 $15.2M 4 Dec 6, 2022 Director, 10%+ Owner
ACRV Acrivon Therapeutics, Inc. Nov 17, 2022 0 $0 3 Nov 18, 2022 10%+ Owner
QTNT Quotient Ltd Oct 31, 2022 1 -$660K 4 Nov 2, 2022 10%+ Owner
ALBO ALBIREO PHARMA, INC. Oct 11, 2022 7 -$9.51M 4 Oct 13, 2022 10%+ Owner
LIAN LianBio Aug 18, 2022 1 $2.4M 4 Aug 22, 2022 Director, 10%+ Owner
CERE Cerevel Therapeutics Holdings, Inc. Aug 16, 2022 2 $150M 4 Aug 18, 2022 Director
ALDX Aldeyra Therapeutics, Inc. Aug 9, 2022 2 $868K 4 Aug 11, 2022 10%+ Owner
ALDX Aldeyra Therapeutics, Inc. Aug 8, 2022 1 $702K 4 Aug 10, 2022 10%+ Owner
ALDX Aldeyra Therapeutics, Inc. Aug 5, 2022 1 $980K 4 Aug 9, 2022 10%+ Owner
ALDX Aldeyra Therapeutics, Inc. Aug 4, 2022 1 $587K 4 Aug 8, 2022 10%+ Owner
ALDX Aldeyra Therapeutics, Inc. Aug 3, 2022 1 $584K 4 Aug 5, 2022 10%+ Owner
ALDX Aldeyra Therapeutics, Inc. Aug 2, 2022 1 $2.31M 4 Aug 4, 2022 10%+ Owner
ALDX Aldeyra Therapeutics, Inc. Aug 1, 2022 1 $728K 4 Aug 3, 2022 10%+ Owner
ALDX Aldeyra Therapeutics, Inc. Jul 29, 2022 1 $1.12M 4 Aug 2, 2022 10%+ Owner
ALDX Aldeyra Therapeutics, Inc. Jul 28, 2022 1 $597K 4 Aug 1, 2022 10%+ Owner
VRCA Verrica Pharmaceuticals Inc. Jul 5, 2022 1 $3M 4 Jul 5, 2022 10%+ Owner
ATHA Athira Pharma, Inc. Jun 29, 2022 2 $4.1M 4 Jul 1, 2022 Director, 10%+ Owner
LIAN LianBio Jun 23, 2022 2 $0 4 Jun 27, 2022 Director, 10%+ Owner
NAUT Nautilus Biotechnology, Inc. Jun 15, 2022 1 $0 4 Jun 17, 2022 Director, 10%+ Owner
MGTX MeiraGTx Holdings plc Jun 7, 2022 2 $0 4 Jun 13, 2022 Director, 10%+ Owner
SLDB Solid Biosciences Inc. Jun 7, 2022 1 $0 4 Jun 9, 2022 Director, 10%+ Owner
LIAN LianBio May 26, 2022 1 $216K 4 May 27, 2022 Director, 10%+ Owner
LIAN LianBio May 23, 2022 3 $442K 4 May 25, 2022 Director, 10%+ Owner
ATHA Athira Pharma, Inc. May 20, 2022 1 $0 4 May 27, 2022 Director, 10%+ Owner
CRNX Crinetics Pharmaceuticals, Inc. Apr 18, 2022 1 $3.5M 4 Apr 18, 2022 10%+ Owner
LYRA Lyra Therapeutics, Inc. Apr 12, 2022 1 $25M 4 Apr 14, 2022 Director, 10%+ Owner
NAUT Nautilus Biotechnology, Inc. Dec 8, 2021 1 $1.07M 4 Dec 10, 2021 Director
VBIV VBI Vaccines Inc/BC Dec 1, 2021 1 -$8.96M 4 Dec 3, 2021 10%+ Owner
LIAN LianBio Nov 3, 2021 2 $36.3M 4 Nov 5, 2021 Director, 10%+ Owner
LIAN LianBio Nov 1, 2021 12 $3.21M 4 Nov 3, 2021 Director, 10%+ Owner
LIAN LianBio Oct 29, 2021 0 $0 3 Oct 29, 2021 Director, 10%+ Owner
CRNX Crinetics Pharmaceuticals, Inc. Oct 25, 2021 1 $23.8M 4 Oct 25, 2021 10%+ Owner
AGRX AGILE THERAPEUTICS INC Oct 13, 2021 2 $4.87M 4 Oct 15, 2021 10%+ Owner
ISO IsoPlexis Corp Oct 12, 2021 7 $12.8M 4 Oct 14, 2021 10%+ Owner
RAIN Rain Therapeutics Inc. Oct 7, 2021 7 -$667K 4 Oct 13, 2021 10%+ Owner
ISO IsoPlexis Corp Oct 7, 2021 0 $0 3 Oct 7, 2021 10%+ Owner
ADMA ADMA BIOLOGICS, INC. Sep 28, 2021 3 -$299K 4 Sep 30, 2021 10%+ Owner
ADMA ADMA BIOLOGICS, INC. Sep 24, 2021 2 -$623K 4 Sep 29, 2021 10%+ Owner
LPTX LEAP THERAPEUTICS, INC. Sep 24, 2021 1 $10M 4 Sep 28, 2021 10%+ Owner
ADMA ADMA BIOLOGICS, INC. Sep 23, 2021 1 -$991K 4 Sep 28, 2021 10%+ Owner
LABP Landos Biopharma, Inc. Aug 27, 2021 1 $0 4 Aug 31, 2021 Director, 10%+ Owner
CERE Cerevel Therapeutics Holdings, Inc. Aug 26, 2021 1 $2.06M 4 Aug 31, 2021 Director
CERE Cerevel Therapeutics Holdings, Inc. Aug 23, 2021 3 $4.83M 4 Aug 25, 2021 Director
ADMA ADMA BIOLOGICS, INC. Aug 17, 2021 3 -$2.33M 4 Aug 19, 2021 10%+ Owner
VYNE VYNE Therapeutics Inc. Aug 16, 2021 1 -$435K 4 Aug 18, 2021 10%+ Owner
VYNE VYNE Therapeutics Inc. Aug 13, 2021 1 -$460K 4 Aug 17, 2021 10%+ Owner
VYNE VYNE Therapeutics Inc. Aug 12, 2021 1 -$756K 4 Aug 16, 2021 10%+ Owner
CERE Cerevel Therapeutics Holdings, Inc. Jul 7, 2021 1 $5M 4 Jul 9, 2021 Director
VBIV VBI Vaccines Inc/BC Jun 29, 2021 2 -$2.46M 4 Jun 30, 2021 10%+ Owner
MGTX MeiraGTx Holdings plc Jun 10, 2021 2 $0 4 Jun 14, 2021 Director, 10%+ Owner
VBIV VBI Vaccines Inc/BC Jun 9, 2021 6 -$1K 4 Jun 11, 2021 10%+ Owner
NAUT ARYA Sciences Acquisition Corp III Jun 3, 2021 1 $3.32M 4 Jun 3, 2021 Director
ATHA Athira Pharma, Inc. May 28, 2021 1 $0 4 Jun 1, 2021 Director
NAUT Nautilus Biotechnology, Inc. May 24, 2021 3 $55.1M 4 Jun 11, 2021 Former Director
NAUT ARYA Sciences Acquisition Corp III May 20, 2021 1 $1.61M 4 May 24, 2021 Director
NAUT ARYA Sciences Acquisition Corp III May 20, 2021 0 $0 3 May 24, 2021 Director
VYNE VYNE Therapeutics Inc. May 6, 2021 1 -$3.67M 4 May 7, 2021 10%+ Owner