| ADGM |
Adagio Medical Holdings, Inc. |
Common Stock, $0.0001 par value per share |
73.6% |
$11.8M |
|
15.3M |
|
Perceptive Advisors LLC |
Dec 31, 2024 |
| TRIB |
Trinity Biotech plc |
Class A Ordinary Shares, $0.0001 par value per share |
22.5% |
$105M |
$15.6M |
101M |
+17.5% |
Perceptive Advisors LLC |
Oct 23, 2025 |
| SLDB |
Solid Biosciences Inc. |
Common Stock, $0.001 par value per share |
15.6% |
$32.2M |
|
11.9M |
|
Perceptive Advisors LLC |
Feb 19, 2025 |
| LYRA |
Lyra Therapeutics, Inc. |
Common Stock, $0.001 par value |
15.55% |
$22.2K |
|
256K |
|
Perceptive Advisors LLC |
Aug 12, 2025 |
| ATXS |
Astria Therapeutics, Inc. |
Common Stock, par value $0.001 per share |
11.5% |
$47.2M |
|
6.49M |
|
Perceptive Advisors LLC |
Oct 14, 2025 |
| NAUT |
Nautilus Biotechnology, Inc. |
Common Stock, $0.0001 par value per share |
10.1% |
$8.84M |
$152K |
12.8M |
+1.75% |
Perceptive Advisors LLC |
Jun 20, 2025 |
| ENGN |
enGene Holdings Inc. |
Common Shares |
9.99% |
$47.1M |
|
6.77M |
|
Perceptive Advisors LLC |
Nov 11, 2025 |
| OBIO |
Orchestra BioMed Holdings, Inc. |
Common Stock, par value $0.0001 per share |
9.99% |
$14.1M |
|
5.68M |
|
Perceptive Advisors LLC |
Sep 30, 2025 |
| PALI |
PALISADE BIO, INC. |
Common Stock, $0.01 par value |
9.99% |
$7.1M |
|
12.2M |
|
Perceptive Advisors LLC |
Oct 2, 2025 |
| IRD |
Opus Genetics, Inc. |
Common Stock, $0.0001 par value per share |
9.99% |
$4.01M |
|
4.51M |
|
Perceptive Advisors LLC |
Mar 24, 2025 |
| TRAW |
Traws Pharma, Inc. |
Common Stock, par value $0.01 per share |
9.99% |
$1.68M |
$646K |
887K |
+62.7% |
Perceptive Advisors LLC |
Sep 30, 2025 |
| OM |
Outset Medical, Inc. |
Common Stock, $0.001 par value per share |
9.5% |
$3.16M |
|
5.63M |
|
Perceptive Advisors LLC |
Jan 8, 2025 |
| ALDX |
Aldeyra Therapeutics, Inc. |
Common Stock, par value $0.001 per share |
8.7% |
$27.3M |
$6.11M |
5.22M |
+28.9% |
Perceptive Advisors LLC |
Sep 30, 2025 |
| AMLX |
Amylyx Pharmaceuticals, Inc. |
Common Stock, $0.0001 par value per share |
8.2% |
$122M |
$14.7M |
8.95M |
+13.7% |
Perceptive Advisors LLC |
Sep 30, 2025 |
| IVVD |
INVIVYD, INC. |
Common Stock, $0.0001 par value per share |
7.9% |
$40.7M |
|
21.8M |
|
Perceptive Advisors LLC |
Nov 18, 2025 |
| XFOR |
X4 PHARMACEUTICALS, INC. |
Common Stock, par value $0.001 per share |
7.6% |
$21M |
|
6.06M |
|
Perceptive Advisors LLC |
Oct 27, 2025 |
| ANRO |
Alto Neuroscience, Inc. |
Common Stock, $0.0001 par value per share |
7.3% |
$7.72M |
|
1.99M |
|
Perceptive Advisors LLC |
Oct 3, 2025 |
| RYTM |
Rhythm Pharmaceuticals, Inc. |
Common Stock, $0.001 par value per share |
6.8% |
$208M |
|
4.42M |
|
Perceptive Advisors LLC |
Mar 31, 2025 |
| OM |
Outset Medical, Inc. |
Common Stock, $0.001 par value per share |
6.7% |
$12.3M |
|
1.21M |
|
Perceptive Advisors LLC |
Mar 31, 2025 |
| PRAX |
Praxis Precision Medicines, Inc. |
Common Stock, par value $0.0001 per share |
6.69% |
$53.1M |
$14.9M |
1.36M |
+38.9% |
Perceptive Advisors LLC |
Jul 15, 2025 |
| CELC |
Celcuity Inc. |
Common Stock, $0.001 par value per share |
6.55% |
$29.5M |
$11.5M |
2.67M |
+63.5% |
Perceptive Advisors LLC |
Jul 30, 2025 |
| DRUG |
Bright Minds Biosciences Inc. |
Common Shares, without par value |
6.3% |
$16M |
|
445K |
|
Perceptive Advisors LLC |
Mar 31, 2025 |
| CTMX |
CytomX Therapeutics, Inc. |
Common Stock, $0.00001 par value per share |
5.9% |
$19.4M |
|
9.68M |
|
Perceptive Advisors LLC |
Aug 14, 2025 |
| TVTX |
TRAVERE THERAPEUTICS, INC. |
Common Stock, par value $0.0001 per share |
5.5% |
$117M |
|
4.9M |
|
Perceptive Advisors LLC |
Oct 6, 2025 |
| BDSX |
Biodesix, Inc. |
Common Stock, par value $0.001 per share |
5.1% |
$4.37M |
$570K |
7.67M |
+15% |
Perceptive Advisors LLC |
May 12, 2025 |
| IVA |
Inventiva S.A. |
Ordinary shares, nominal value euro 0.01 per share |
4.99% |
$40.3M |
$9.63M |
7.3M |
+31.4% |
Perceptive Advisors LLC |
Sep 30, 2025 |
| AVR |
Anteris Technologies Global Corp. |
Common Stock, par value $0.0001 per share |
4.7% |
$6.31M |
-$2.72M |
1.71M |
-30.1% |
Perceptive Advisors LLC |
Jun 30, 2025 |
| ACLX |
Arcellx, Inc. |
Common Stock, par value $0.001 per share |
4.5% |
$184M |
-$33.2M |
2.48M |
-15.3% |
Perceptive Advisors LLC |
Jun 30, 2025 |
| RAPT |
RAPT Therapeutics, Inc. |
Common Stock, $0.0001 par value per share |
4.5% |
$5M |
|
5.88M |
|
Perceptive Advisors LLC |
Dec 31, 2024 |
| EWTX |
Edgewise Therapeutics, Inc. |
Common Stock, par value $0.0001 per share |
4.4% |
$68M |
-$25.7M |
4.64M |
-27.5% |
Perceptive Advisors LLC |
Jun 30, 2025 |
| SYRE |
Spyre Therapeutics, Inc. |
Common Stock, $0.0001 par value per share |
4.4% |
$31.5M |
-$186M |
2.57M |
-79.6% |
Perceptive Advisors LLC |
Dec 31, 2024 |
| AORT |
ARTIVION, INC. |
Common Stock, $0.01 par value |
4.3% |
$85.5M |
|
2.02M |
|
Perceptive Advisors LLC |
Sep 30, 2025 |
| IOVA |
Iovance Biotherapeutics, Inc. |
Common Stock, par value $0.000041666 per share |
3.8% |
$42.3M |
-$30.7M |
12.8M |
-42.1% |
Perceptive Advisors LLC |
Mar 31, 2025 |
| EOLS |
Evolus, Inc. |
Common Stock, $0.00001 par value per share |
3.8% |
$18.8M |
-$12.5M |
2.47M |
-40.1% |
Perceptive Advisors LLC |
Jun 30, 2025 |
| ENSC |
Ensysce Biosciences, Inc. |
Common Stock, par value $0.0001 per share |
3.7% |
$176K |
|
86.7K |
0% |
Perceptive Advisors LLC |
Mar 31, 2025 |
| BBNX |
Beta Bionics, Inc. |
Common Stock, $0.0001 par value per share |
3.68% |
$23.8M |
|
1.59M |
|
Perceptive Advisors LLC |
Mar 31, 2025 |
| CTNM |
Contineum Therapeutics, Inc. |
Class A Common Stock, par value $0.001 per share |
3.2% |
$7.03M |
-$7.45M |
699K |
-51.5% |
Perceptive Advisors LLC |
Jun 30, 2025 |
| CRGX |
CARGO Therapeutics, Inc. |
Common Stock, $0.001 par value per share |
2.5% |
$4.74M |
|
1.17M |
|
Perceptive Advisors LLC |
Apr 23, 2025 |
| FBRX |
Forte Biosciences, Inc. |
Common Stock, par value $0.001 per share |
2.5% |
$875K |
|
164K |
|
Perceptive Advisors LLC |
Dec 31, 2024 |
| FOLD |
Amicus Therapeutics, Inc. |
Common Stock, par value $0.01 per share |
2.4% |
$54.9M |
-$104M |
7.41M |
-65.5% |
Perceptive Advisors LLC |
Jun 30, 2025 |
| APLT |
Applied Therapeutics, Inc. |
Common Stock, $0.0001 par value per share |
2.4% |
$915K |
|
2.86M |
|
Perceptive Advisors LLC |
Dec 31, 2024 |
| SRZN |
Surrozen, Inc. |
Common Stock, $0.0001 par value per share |
1.9% |
$1.94M |
|
167K |
0% |
Perceptive Advisors LLC |
Mar 31, 2025 |
| VRCA |
Verrica Pharmaceuticals, Inc. |
Common Stock, $0.0001 par value per share |
1.6% |
$711K |
-$1.56M |
1.48M |
-68.7% |
Perceptive Advisors LLC |
Mar 31, 2025 |
| ACRV |
Acrivon Therapeutics, Inc. |
Common Stock, par value $0.001 per share |
0% |
$0 |
-$4.13M |
0 |
-100% |
Perceptive Advisors LLC |
Jun 2, 2025 |
| VRNA |
Verona Pharma plc |
Ordinary shares, nominal value GBP 0.05 per share |
0% |
$0 |
-$588M |
0 |
-100% |
Perceptive Advisors LLC |
Sep 30, 2025 |
| KALA |
KALA BIO, Inc. |
Common Stock, par value $0.001 per share |
0% |
$0 |
-$860K |
0 |
-100% |
Perceptive Advisors LLC |
Sep 30, 2025 |
| LYRA |
Lyra Therapeutics, Inc. |
Common Stock, $0.001 par value |
0% |
$0 |
-$596K |
0 |
-100% |
Perceptive Advisors LLC |
Nov 21, 2025 |
| TIL |
Instil Bio, Inc. |
Common Stock, par value $0.000001 per share |
0% |
$0 |
|
0 |
|
Perceptive Advisors LLC |
Mar 31, 2025 |
| OKUR |
OnKure Therapeutics, Inc. |
Common Stock, par value $0.0001 per share |
|
$0 |
|
0 |
|
Perceptive Advisors LLC |
Jun 30, 2025 |