Significant Ownership of PERCEPTIVE ADVISORS LLC

Signature - Title
/s/ Joseph Edelman - Joseph Edelman, Managing Member
Location
New York, NY
Summary
This page shows a list of all the recent SCHEDULE 13D/G filings made by PERCEPTIVE ADVISORS LLC.

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Significant Ownership of PERCEPTIVE ADVISORS LLC

Sym Company Class Ownership Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
ADGM Adagio Medical Holdings, Inc. Common Stock, $0.0001 par value per share 74% $11,797,674 15,321,655 Perceptive Advisors LLC 31 Dec 2024
ATHA LeonaBio, Inc. Common Stock, $0.0001 par value 20% $13,052,440 -$68,291 1,859,322 -0.52% Perceptive Advisors LLC 16 Jan 2026
SLDB Solid Biosciences Inc. Common Stock, $0.001 par value per share 16% $32,223,633 11,934,679 Perceptive Advisors LLC 19 Feb 2025
LYRA Lyra Therapeutics, Inc. Common Stock, $0.001 par value 16% $22,174 255,750 Perceptive Advisors LLC 12 Aug 2025
MGTX MeiraGTx Holdings plc Ordinary Shares, nominal value $0.00003881 per share 13% $85,934,055 10,441,562 Perceptive Advisors LLC 31 Dec 2025
ATXS Astria Therapeutics, Inc. Common Stock, par value $0.001 per share 12% $47,213,858 6,485,420 Perceptive Advisors LLC 14 Oct 2025
NAUT Nautilus Biotechnology, Inc. Common Stock, $0.0001 par value per share 10% $8,842,428 +$152,422 12,815,113 +1.8% Perceptive Advisors LLC 20 Jun 2025
ENGN enGene Holdings Inc. Common Shares 10% $47,123,411 6,770,605 Perceptive Advisors LLC 11 Nov 2025
OBIO Orchestra BioMed Holdings, Inc. Common Stock, par value $0.0001 per share 10% $14,085,110 5,679,480 Perceptive Advisors LLC 30 Sep 2025
PALI PALISADE BIO, INC. Common Stock, $0.01 par value 10% $7,100,950 12,243,018 Perceptive Advisors LLC 02 Oct 2025
IRD Opus Genetics, Inc. Common Stock, $0.0001 par value per share 10% $4,014,346 4,510,501 Perceptive Advisors LLC 24 Mar 2025
TRAW Traws Pharma, Inc. Common Stock, par value $0.01 per share 10% $1,676,216 +$645,794 886,887 +63% Perceptive Advisors LLC 30 Sep 2025
TRIB Trinity Biotech plc Class A Ordinary Shares, $0.0001 par value per share 9.9% $1,468,881,086 +$1,370,097,086 1,498,858,251 +1387% Perceptive Advisors LLC 22 Dec 2025
OM Outset Medical, Inc. Common Stock, $0.001 par value per share 9.5% $3,164,062 5,625,000 Perceptive Advisors LLC 08 Jan 2025
ALDX Aldeyra Therapeutics, Inc. Common Stock, par value $0.001 per share 8.7% $27,260,463 +$6,110,950 5,222,311 +29% Perceptive Advisors LLC 30 Sep 2025
AMLX Amylyx Pharmaceuticals, Inc. Common Stock, $0.0001 par value per share 8.2% $121,662,640 +$14,650,251 8,952,365 +14% Perceptive Advisors LLC 30 Sep 2025
IVVD INVIVYD, INC. Common Stock, $0.0001 par value per share 7.9% $40,738,260 21,785,166 Perceptive Advisors LLC 18 Nov 2025
XFOR X4 PHARMACEUTICALS, INC. Common Stock, par value $0.001 per share 7.6% $20,980,760 6,064,680 Perceptive Advisors LLC 27 Oct 2025
ANRO Alto Neuroscience, Inc. Common Stock, $0.0001 par value per share 7.3% $7,718,845 1,989,393 Perceptive Advisors LLC 03 Oct 2025
TENX Tenax Therapeutics, Inc. Common Stock, $0.0001 par value per share 7% $4,158,675 439,142 Perceptive Advisors LLC 18 Dec 2025
RYTM Rhythm Pharmaceuticals, Inc. Common Stock, $0.001 par value per share 6.8% $207,680,555 4,423,441 Perceptive Advisors LLC 31 Mar 2025
OM Outset Medical, Inc. Common Stock, $0.001 par value per share 6.7% $12,276,673 1,208,334 Perceptive Advisors LLC 31 Mar 2025
PRAX Praxis Precision Medicines, Inc. Common Stock, par value $0.0001 per share 6.7% $53,083,117 +$14,867,487 1,362,503 +39% Perceptive Advisors LLC 15 Jul 2025
CELC Celcuity Inc. Common Stock, $0.001 par value per share 6.6% $29,483,391 +$11,452,775 2,670,597 +64% Perceptive Advisors LLC 30 Jul 2025
DRUG Bright Minds Biosciences Inc. Common Shares, without par value 6.3% $16,038,489 444,649 Perceptive Advisors LLC 31 Mar 2025
CTMX CytomX Therapeutics, Inc. Common Stock, $0.00001 par value per share 5.9% $19,360,370 9,680,185 Perceptive Advisors LLC 14 Aug 2025
TVTX TRAVERE THERAPEUTICS, INC. Common Stock, par value $0.0001 per share 5.5% $117,005,198 4,895,615 Perceptive Advisors LLC 06 Oct 2025
BDSX Biodesix, Inc. Common Stock, par value $0.001 per share 5.1% $4,374,112 +$570,000 7,673,880 +15% Perceptive Advisors LLC 12 May 2025
IVA Inventiva S.A. Ordinary shares, nominal value euro 0.01 per share 5% $40,299,676 +$9,633,013 7,300,666 +31% Perceptive Advisors LLC 30 Sep 2025
AVR Anteris Technologies Global Corp. Common Stock, par value $0.0001 per share 4.7% $6,308,981 -$2,719,019 1,705,130 -30% Perceptive Advisors LLC 30 Jun 2025
ACLX Arcellx, Inc. Common Stock, par value $0.001 per share 4.5% $183,570,240 -$33,223,250 2,478,000 -15% Perceptive Advisors LLC 30 Jun 2025
RAPT RAPT Therapeutics, Inc. Common Stock, $0.0001 par value per share 4.5% $4,998,000 5,880,000 Perceptive Advisors LLC 31 Dec 2024
EWTX Edgewise Therapeutics, Inc. Common Stock, par value $0.0001 per share 4.4% $67,975,253 -$25,719,496 4,639,949 -27% Perceptive Advisors LLC 30 Jun 2025
SYRE Spyre Therapeutics, Inc. Common Stock, $0.0001 par value per share 4.4% $31,463,115 -$185,961,697 2,574,723 -80% Perceptive Advisors LLC 31 Dec 2024
AORT ARTIVION, INC. Common Stock, $0.01 par value 4.3% $85,526,800 2,020,000 Perceptive Advisors LLC 30 Sep 2025
IOVA Iovance Biotherapeutics, Inc. Common Stock, par value $0.000041666 per share 3.8% $42,269,000 -$30,701,477 12,808,788 -42% Perceptive Advisors LLC 31 Mar 2025
EOLS Evolus, Inc. Common Stock, $0.00001 par value per share 3.8% $18,759,310 -$12,539,586 2,474,843 -40% Perceptive Advisors LLC 30 Jun 2025
ENSC Ensysce Biosciences, Inc. Common Stock, par value $0.0001 per share 3.7% $175,932 86,666 0% Perceptive Advisors LLC 31 Mar 2025
BBNX Beta Bionics, Inc. Common Stock, $0.0001 par value per share 3.7% $23,760,695 1,593,608 Perceptive Advisors LLC 31 Mar 2025
CTNM Contineum Therapeutics, Inc. Class A Common Stock, par value $0.001 per share 3.2% $7,029,834 -$7,454,718 699,486 -51% Perceptive Advisors LLC 30 Jun 2025
CRGX CARGO Therapeutics, Inc. Common Stock, $0.001 par value per share 2.5% $4,741,780 1,170,810 Perceptive Advisors LLC 23 Apr 2025
FBRX Forte Biosciences, Inc. Common Stock, par value $0.001 per share 2.5% $875,413 163,935 Perceptive Advisors LLC 31 Dec 2024
FOLD Amicus Therapeutics, Inc. Common Stock, par value $0.01 per share 2.4% $54,854,942 -$103,982,558 7,412,830 -65% Perceptive Advisors LLC 30 Jun 2025
APLT Applied Therapeutics, Inc. Common Stock, $0.0001 par value per share 2.4% $915,200 2,860,000 Perceptive Advisors LLC 31 Dec 2024
SRZN Surrozen, Inc. Common Stock, $0.0001 par value per share 1.9% $1,943,326 166,666 0% Perceptive Advisors LLC 31 Mar 2025
VRCA Verrica Pharmaceuticals, Inc. Common Stock, $0.0001 par value per share 1.6% $711,111 -$1,559,841 1,481,481 -69% Perceptive Advisors LLC 31 Mar 2025
TIL Instil Bio, Inc. Common Stock, par value $0.000001 per share 0% $0 0 Perceptive Advisors LLC 31 Mar 2025
KALA KALA BIO, Inc. Common Stock, par value $0.001 per share 0% $0 -$860,368 0 -100% Perceptive Advisors LLC 30 Sep 2025
LYRA Lyra Therapeutics, Inc. Common Stock, $0.001 par value 0% $0 -$595,704 0 -100% Perceptive Advisors LLC 21 Nov 2025
ACRV Acrivon Therapeutics, Inc. Common Stock, par value $0.001 per share 0% $0 -$4,128,505 0 -100% Perceptive Advisors LLC 02 Jun 2025
VRNA Verona Pharma plc Ordinary shares, nominal value GBP 0.05 per share 0% $0 -$587,715,036 0 -100% Perceptive Advisors LLC 30 Sep 2025
OKUR OnKure Therapeutics, Inc. Common Stock, par value $0.0001 per share $0 0 Perceptive Advisors LLC 30 Jun 2025

Schedules 13D/G Reported by PERCEPTIVE ADVISORS LLC:

Sym Target Class Ownership Change Current Shares Change Value Reporting name Form Report Period Filing Date
* An asterisk sign (*) next to the price indicates that the price is likely invalid.