Type / Class
Equity / Common Stock, par value $0.001 per share
Shares outstanding
54,284,692
Total 13F shares
48,353,677
Share change
+2,883,110
Total reported value
$530,923,062
Price per share
$10.98
Number of holders
82
Value change
+$32,738,817
Number of buys
53
Number of sells
22

Institutional Holders of Upstream Bio, Inc. - Common Stock, par value $0.001 per share (UPB) as of Q2 2025

As of 30 Jun 2025, Upstream Bio, Inc. - Common Stock, par value $0.001 per share (UPB) was held by 82 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 48,353,677 shares. The largest 10 holders included FMR LLC, ORBIMED ADVISORS LLC, Altshuler Shaham Ltd, Decheng Capital LLC, TCG Crossover Management, LLC, ENAVATE SCIENCES GP, LLC, Bain Capital Life Sciences Investors, LLC, VR ADVISER, LLC, VANGUARD GROUP INC, and BlackRock, Inc.. This page lists 82 institutional shareholders reporting positions in this security for the Q2 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.