Type / Class
Equity / Common Stock, par value $0.001 per share
Shares outstanding
54,284,692
Total 13F shares
5,349,566
Share change
+2,609,059
Total reported value
$145,240,689
Price per share
$27.15
Number of holders
29
Value change
+$70,836,142
Number of buys
21
Number of sells
5

Institutional Holders of Upstream Bio, Inc. - Common Stock, par value $0.001 per share (UPB) as of Q4 2025

As of 31 Dec 2025, Upstream Bio, Inc. - Common Stock, par value $0.001 per share (UPB) was held by 29 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 5,349,566 shares. The largest 10 holders included VANGUARD GROUP INC, UBS Group AG, Pictet Asset Management Holding SA, JENNISON ASSOCIATES LLC, PSP Research LLC, PROFUND ADVISORS LLC, DNB Asset Management AS, STRS OHIO, China Universal Asset Management Co., Ltd., and ProShare Advisors LLC. This page lists 29 institutional shareholders reporting positions in this security for the Q4 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.