Dominic Smethurst - 23 Sep 2021 Form 4 Insider Report for BICYCLE THERAPEUTICS plc (BCYC)

Role: Chief Medical Officer
Signature: /s/ Lee Kalowski, as Attorney-in-Fact
Issuer symbol: BCYC
Transactions as of: 23 Sep 2021
Transactions value $: $111,300
Form type: 4
Filing time: 27 Sep 2021, 16:53:08
Next filing: 05 Jan 2022
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	BCYC	Ordinary Shares	Options Exercise	$111K	+6K		$18.55	6K	23 Sep 2021	Direct

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	BCYC	Employee Stock Option (right to buy)	Options Exercise	$0	-6K	-5%	$0.00	114K	23 Sep 2021	Ordinary Shares	6K	$18.55	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	This option vested one-fourth (1/4) of the total number of shares on August 10, 2021 and the remaining shares shall vest or vested in 36 equal monthly installments at the end of each calendar month thereafter.