| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| Perceptive Advisors LLC | 8.2% | 8.95M | 0 | 8.95M | /s/ Joseph Edelman | Joseph Edelman, Managing Member | |
| Joseph Edelman | 8.2% | 8.95M | 0 | 8.95M | /s/ Joseph Edelman | Joseph Edelman | |
| Perceptive Life Sciences Master Fund, Ltd. | 8.2% | 8.95M | 0 | 8.95M | /s/ Joseph Edelman | Joseph Edelman, Managing Member |