| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 14% | 20,464,738 | 0 | 20,464,738 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 5.1% | 7,384,314 | 0 | 7,384,314 | Kristin Mariani | Head of North America Compliance, CCO |