| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 14% | 20,788,363 | 0 | 20,788,363 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 5.1% | 7,392,199 | 0 | 7,392,199 | Kristin Mariani | Head of North America Compliance, CCO |