Perceptive Advisors Llc

13F Holdings History for Amylyx Pharmaceuticals, Inc. - Common Stock, $0.0001 par value per share (AMLX)

Symbol: AMLX on Nasdaq
Investment type: Equity / Common Stock, $0.0001 par value per share
Latest Disclosed Ownership: 8.95M shares
Security Ownership: 8.2%

Shares, Excluding Options vs Price

Value, Excluding Options

Perceptive Advisors LLC ownership in Amylyx Pharmaceuticals, Inc. Common Stock, $0.0001 par value per share (AMLX)

2025-11-14 - Perceptive Advisors LLC has filed an SCHEDULE 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 8.95M shares of Amylyx Pharmaceuticals, Inc. Common Stock, $0.0001 par value per share (AMLX). This represents 8.2% percent ownership of the company. In their previous filing dated 2025-05-15, PERCEPTIVE ADVISORS LLC had reported owning 7.87M shares, indicating an increase of 13.7% percent.

Reporting Name	Ownership %	Change	Value $	Shares owned	Change	Activity %	Price	Form	Report date	Filed at
Perceptive Advisors LLC	8.2%	-6.67%	$122M	8.95M	+1,078,017	+13.7%	$13.59	13G/A	9/30/2025	14 Nov 2025 16:00:03
Perceptive Advisors LLC	8.8%	+11.3%	$27.5M	7.87M	+1,100,000	+16.2%	$3.49	13G/A	3/31/2025	15 May 2025 16:30:21
Perceptive Advisors LLC	7.9%		$23.6M	6.77M			$3.49	13G/A	12/31/2024	14 Feb 2025 16:15:06

Holdings date	Option	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
9/30/2025		3.56%	+0.42%	$122M	8.95M	+1,050,000	+13.3%	$13.59	Q3 2025
6/30/2025		1.9%	+0.01%	$50.7M	7.9M	+28,017	+0.36%	$6.41	Q2 2025
3/31/2025		0.99%	+0.14%	$27.9M	7.87M	+1,100,000	+16.2%	$3.54	Q1 2025
12/31/2024		0.71%	+0.49%	$25.6M	6.77M	+4,648,699	+219%	$3.78	Q4 2024
9/30/2024		0.15%	+0.15%	$6.89M	2.13M	+2,125,649	NEW	$3.24	Q3 2024
6/30/2024			-0.02%	$0	0	-300,000	-100%		Q2 2024
6/30/2024	call		-11.6%	$0	0	-1,679,125	-100%		Q2 2024
3/31/2024		0.02%	-0.1%	$852K	300K	-1,569,125	-83.9%	$2.84	Q1 2024
3/31/2024	call	11.6%		$4.77M	1.68M	+1,679,125	NEW	$2.84	Q1 2024
12/31/2023		0.62%	-0.4%	$27.5M	1.87M	-819,748	-30.5%	$14.72	Q4 2023
9/30/2023		1.64%	-1.34%	$49.2M	2.69M	-2,185,046	-44.8%	$18.31	Q3 2023
6/30/2023		3.04%	-0.72%	$105M	4.87M	-1,160,725	-19.2%	$21.57	Q2 2023
3/31/2023		5.23%	-0.05%	$177M	6.03M	-53,689	-0.88%	$29.34	Q1 2023
12/31/2022		6.32%	+0.64%	$225M	6.09M	+616,300	+11.3%	$36.95	Q4 2022
9/30/2022		4.47%	+1.58%	$154M	5.47M	+1,931,625	+54.6%	$28.15	Q3 2022
6/30/2022		2.14%	+1.25%	$68.2M	3.54M	+2,066,301	+140%	$19.26	Q2 2022
3/31/2022		0.38%	+0.38%	$18.9M	1.47M	+1,474,107	NEW	$12.85	Q1 2022

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.