Opaleye Management Inc. - Significant Ownership

Signature - Title
/s/ James Silverman - President
Location
Boston, MA
Summary
This page shows a list of all the recent SCHEDULE 13D/G filings made by Opaleye Management Inc..

Significant Ownership of Opaleye Management Inc.

Sym Company Class Ownership Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
SLGL Sol-Gel Technologies Ltd Ordinary Shares, par value NIS 1.00 per share. 13.19% $13.5M $5.96M 367K +79.3% Opaleye Management Inc. Nov 13, 2025
KPTI Karyopharm Therapeutics Inc. Common Stock, no par value 9.48% $10.3M 1.57M Opaleye Management Inc. Oct 10, 2025
ACOG Alpha Cognition Inc. Common Stock, no par value 8.97% $15M 1.88M Opaleye Management Inc. Oct 1, 2025
IBIO iBio, Inc. Common Stock, par value $0.001 per share 7.6% $900K 750K Opaleye Management, Inc. Dec 31, 2024
LRMR Larimar Therapeutics, Inc. Common Stock 4.8% $16M $615K 4.11M +3.99% Opaleye Management, Inc. Aug 29, 2025
TARA Protara Therapeutics, Inc. Common Stock 4.71% $6.75M -$371K 1.73M -5.21% Opaleye Management, Inc. Mar 31, 2025
OCUL OCULAR THERAPEUTIX, INC Common Stock, par value $0.0001 per share 2.76% $30.4M 4.34M Opaleye Management Inc. Dec 31, 2024
CNTX Context Therapeutics Inc. Common Stock, par value $0.001 per share 0% $0 0 Opaleye Management Inc. Dec 31, 2024

Schedules 13D/G Reported by Opaleye Management Inc.:

Sym Target Class Ownership Change Current Shares Change Value Reporting name Form Report Period Date Filed
* An asterisk sign (*) next to the price indicates that the price is likely invalid.