| CCCC |
C4 Therapeutics, Inc. |
Common Stock, par value $0.0001 per share |
9.9% |
$50,277,776 |
|
22,647,647 |
|
Point72 Asset Management, L.P. |
17 Oct 2025 |
| CYBN |
CYBIN INC. |
Common Shares, no par value |
9.9% |
$37,759,482 |
+$28,298,275 |
6,410,778 |
+299% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| PTNT |
PALATIN TECHNOLOGIES INC |
Common Stock, par value $0.01 per share |
9.9% |
$23,646,750 |
|
2,307,000 |
|
Point72 Asset Management, L.P. |
12 Nov 2025 |
| FGNX |
FG Nexus Inc. |
Common Stock, par value $0.001 per share |
9.9% |
$23,560,000 |
+$3,092,250 |
4,000,000 |
+15% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| IBIO |
iBio, Inc. |
Common Stock, par value $0.001 per share |
9.9% |
$11,288,403 |
|
14,289,118 |
|
Point72 Asset Management, L.P. |
22 Aug 2025 |
| XLO |
Xilio Therapeutics, Inc. |
Common Stock, par value $0.0001 per share |
9.9% |
$6,752,000 |
+$3,376,000 |
8,000,000 |
+100% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| IVVD |
Invivyd, Inc. |
Common Stock, par value $0.0001 per share |
9.7% |
$22,409,727 |
+$4,006,213 |
20,372,479 |
+22% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| PRAX |
Praxis Precision Medicines, Inc. |
Common Stock, par value $0.0001 per share |
9.6% |
$109,866,297 |
+$28,721,283 |
2,072,949 |
+35% |
Steven A. Cohen |
30 Sep 2025 |
| TNXP |
Tonix Pharmaceuticals Holding Corp. |
Common Stock, par value $0.001 per share |
9.2% |
$19,884,434 |
|
1,235,058 |
|
Point72 Asset Management, L.P. |
29 Dec 2025 |
|
Aptevo Therapeutics Inc. |
Common Stock, par value $0.001 per share |
9.1% |
|
|
299,944 |
|
Point72 Asset Management, L.P. |
16 Sep 2025 |
| KRRO |
Korro Bio, Inc. |
Common Stock, par value $0.001 per share |
8.7% |
$19,336,141 |
|
816,905 |
|
Steven A. Cohen |
30 Jun 2025 |
|
1RT Acquisition Corp. |
Class A Ordinary Shares, par value $0.0001 per share |
8.7% |
|
|
1,500,000 |
|
Point72 Asset Management, L.P. |
03 Jul 2025 |
| AVTX |
Avalo Therapeutics, Inc. |
Common Stock, par value $0.001 per share |
8% |
$13,396,124 |
+$5,914,611 |
1,053,983 |
+79% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| RLAY |
Relay Therapeutics, Inc. |
Common Stock, par value $0.001 per share |
7.8% |
$47,463,335 |
+$13,242,749 |
13,445,704 |
+39% |
Point72 Asset Management, L.P. |
30 Jun 2025 |
| ANAB |
ANAPTYSBIO, INC |
Common Stock, par value $0.001 per share |
7.7% |
$40,664,913 |
+$11,624,056 |
2,368,370 |
+40% |
Point72 Asset Management, L.P. |
31 Mar 2025 |
| ZEPP |
Zepp Health Corp |
Class A Ordinary Shares, par value $0.0001 per share |
7.6% |
$401,811,426 |
+$105,513,012 |
8,777,008 |
+36% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| TENX |
TENAX THERAPEUTICS, INC. |
Common Stock, par value $0.0001 per share |
7.4% |
$2,037,798 |
|
339,633 |
|
Point72 Asset Management, L.P. |
22 Oct 2025 |
| ADCT |
ADC Therapeutics SA |
Common Shares, par value CHF 0.08 per share |
7% |
$10,494,110 |
|
7,831,425 |
|
Point72 Asset Management, L.P. |
16 Jun 2025 |
| ANRO |
Alto Neuroscience, Inc. |
Common Stock, par value $0.0001 per share |
7% |
$4,063,680 |
-$962,973 |
1,907,831 |
-19% |
Steven A. Cohen |
31 Mar 2025 |
| CLDX |
Celldex Therapeutics, Inc. |
Common Stock, par value $0.001 per share |
6.7% |
$84,421,804 |
|
4,464,400 |
|
Point72 Asset Management, L.P. |
02 Jul 2025 |
| PLRX |
PLIANT THERAPEUTICS, INC. |
Common Stock, par value $0.0001 per share |
6.7% |
$6,617,728 |
|
4,085,017 |
|
Point72 Asset Management, L.P. |
27 Aug 2025 |
| GLTO |
Galecto, Inc. |
Common Stock, par value $0.00001 per share |
6.3% |
$380,004 |
|
100,001 |
|
Point72 Asset Management, L.P. |
12 Nov 2025 |
| CDTX |
Cidara Therapeutics, Inc. |
Common Stock, par value $0.0001 per share |
6.2% |
$151,115,887 |
+$4,801,311 |
1,578,069 |
+3.3% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| WWW |
WOLVERINE WORLD WIDE INC /DE/ |
Common Stock, par value $1 per share |
6.2% |
$139,279,403 |
+$27,481,325 |
5,075,780 |
+25% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| ANGO |
ANGIODYNAMICS INC |
Common Stock, par value $0.01 per share |
6.2% |
$28,588,375 |
+$4,905,719 |
2,559,389 |
+21% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| PALI |
PALISADE BIO, INC. |
Common Stock, par value $0.01 per share |
6.2% |
$4,399,654 |
|
7,585,611 |
|
Point72 Asset Management, L.P. |
06 Oct 2025 |
| VSTM |
Verastem, Inc. |
Common Stock, par value $0.0001 per share |
6.1% |
$24,904,606 |
|
3,338,419 |
|
Point72 Asset Management, L.P. |
25 Jul 2025 |
| CFLT |
Confluent, Inc. |
Class A Common Stock, par value $0.00001 per share |
6% |
$347,129,897 |
+$60,803,978 |
17,531,813 |
+21% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
|
WOLFSPEED, INC. |
Common Stock, par value $0.00125 per share |
6% |
|
|
1,545,987 |
|
Steven A. Cohen |
09 Oct 2025 |
| IMNM |
Immunome Inc. |
Common Stock, par value $0.0001 per share |
5.9% |
$34,698,481 |
|
4,887,110 |
|
Point72 Asset Management, L.P. |
31 Jan 2025 |
| PAGS |
PagSeguro Digital Ltd. |
Class A Common Shares, par value $0.000025 per share |
5.7% |
$101,471,520 |
-$22,999,590 |
10,147,152 |
-18% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| MSGE |
Madison Square Garden Entertainment Corp. |
Class A Common Stock, par value $0.01 per share |
5.5% |
$67,938,784 |
|
2,239,248 |
|
Point72 Asset Management, L.P. |
31 Dec 2024 |
| KOD |
Kodiak Sciences Inc. |
Common Stock, par value $0.0001 per share |
5.5% |
$28,244,798 |
|
2,908,836 |
|
Point72 Asset Management, L.P. |
15 Aug 2025 |
| BRCB |
Black Rock Coffee Bar, Inc. |
Class A Common Stock, par value $0.00001 per share |
5.4% |
$22,629,182 |
|
948,415 |
|
Steven A. Cohen |
12 Nov 2025 |
| IPSC |
Century Therapeutics, Inc. |
Common Stock, par value $0.0001 per share |
5.4% |
$2,504,589 |
|
4,725,639 |
|
Point72 Asset Management, L.P. |
23 Dec 2025 |
| DNTH |
Dianthus Therapeutics, Inc. /DE/ |
Common Stock, par value $0.001 per share |
5.3% |
$39,962,278 |
+$4,273,590 |
2,121,140 |
+12% |
Point72 Asset Management, L.P. |
11 Sep 2025 |
| DSGN |
Design Therapeutics, Inc. |
Common Stock, par value $0.0001 per share |
5.2% |
$16,596,935 |
|
2,942,719 |
|
Point72 Asset Management, L.P. |
27 Aug 2025 |
| LION |
Lionsgate Studios Corp. |
Common Shares, no par value per share |
5.1% |
$101,210,670 |
|
14,668,213 |
|
Point72 Asset Management, L.P. |
31 Oct 2025 |
| ORIC |
Oric Pharmaceuticals, Inc. |
Common Stock, par value $0.0001 per share |
5.1% |
$45,161,021 |
|
4,401,659 |
|
Point72 Asset Management, L.P. |
29 May 2025 |
| OVID |
Ovid Therapeutics Inc. |
Common Stock, par value $0.001 per share |
5.1% |
$11,099,895 |
|
6,727,209 |
|
Point72 Asset Management, L.P. |
02 Jan 2026 |
| BILL |
BILL Holdings, Inc. |
Common Stock, par value $0.00001 per share |
5% |
$247,450,711 |
|
5,035,627 |
|
Point72 Asset Management, L.P. |
21 Nov 2025 |
| RUN |
Sunrun Inc. |
Common Stock, par value $0.0001 per share |
5% |
$136,891,257 |
|
11,503,467 |
|
Point72 Asset Management, L.P. |
26 Jun 2025 |
| IDYA |
IDEAYA Biosciences, Inc. |
Common Stock, par value $0.0001 per share |
5% |
$80,218,014 |
|
4,412,432 |
|
Point72 Asset Management, L.P. |
06 Jun 2025 |
| SNDX |
Syndax Pharmaceuticals Inc |
Common Stock, par value $0.0001 per share |
5% |
$66,650,461 |
+$31,109,971 |
4,327,952 |
+88% |
Point72 Asset Management, L.P. |
15 Aug 2025 |
| LENZ |
LENZ Therapeutics, Inc. |
Common Stock, par value $0.00001 per share |
4.8% |
$63,244,042 |
|
1,357,751 |
|
Steven A. Cohen |
30 Sep 2025 |
| REPL |
Replimune Group, Inc. |
Common Stock, par value $0.001 per share |
4.7% |
$15,209,289 |
-$3,488,586 |
3,629,902 |
-19% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| LLYVA |
Liberty Media Corp |
Series A Liberty Live Common Stock, par value $0.01 per share |
4.6% |
$77,719,964 |
|
1,164,693 |
|
Point72 Asset Management, L.P. |
31 Dec 2024 |
| VTYX |
Ventyx Biosciences, Inc. |
Common Stock, par value $0.0001 per share |
4.5% |
$9,982,638 |
-$8,352,206 |
3,209,645 |
-46% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| RCUS |
Arcus Biosciences, Inc. |
Common Stock, par value $0.0001 per share |
4.1% |
$58,921,714 |
-$20,381,232 |
4,332,479 |
-26% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| COGT |
Cogent Biosciences, Inc. |
Common Stock, par value $0.001 per share |
4% |
$82,625,042 |
-$60,775,814 |
5,753,833 |
-42% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| ALTS |
ALT5 Sigma Corp |
Common Stock, par value $0.001 per share |
4% |
|
|
4,872,756 |
|
Point72 Asset Management, L.P. |
11 Aug 2025 |
| STNE |
StoneCo Ltd. |
Class A Common Shares, par value US$0.000079365 per share |
3.9% |
$165,537,092 |
-$68,694,386 |
9,972,114 |
-29% |
Point72 Asset Management, L.P. |
30 Jun 2025 |
| BCYC |
BICYCLE THERAPEUTICS PLC |
Ordinary Shares, nominal value 0.01 GBP per share |
3.9% |
$14,287,235 |
-$14,430,728 |
1,860,317 |
-50% |
Point72 Asset Management, L.P. |
30 Jun 2025 |
| TDOC |
Teladoc Health, Inc. |
Common Stock, par value $0.001 per share |
3.3% |
$44,796,726 |
-$23,430,960 |
5,795,178 |
-34% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| ATYR |
aTYR PHARMA INC |
Common Stock, par value $0.001 per share |
3.2% |
$8,109,259 |
|
2,845,354 |
|
Point72 Asset Management, L.P. |
31 Mar 2025 |
| PEPG |
PepGen Inc. |
Common Stock, par value $0.0001 per share |
3% |
$10,167,217 |
-$2,992,506 |
2,067,432 |
-23% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| DRUG |
BRIGHT MINDS BIOSCIENCES INC. |
Common Shares, without par value |
3% |
$4,876,267 |
|
135,189 |
|
Point72 Asset Management, L.P. |
31 Dec 2024 |
| MBLY |
Mobileye Global Inc. |
Class A Common Stock, par value $0.01 per share |
2.8% |
$84,823,217 |
-$3,371,672 |
6,007,310 |
-3.8% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| TSEM |
TOWER SEMICONDUCTOR LTD |
Ordinary Shares, par value NIS 15.00 per share |
2.6% |
$206,369,650 |
-$252,010,688 |
2,854,352 |
-55% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| AMLX |
Amylyx Pharmaceuticals, Inc. |
Common Stock, par value $0.0001 per share |
2.6% |
$38,074,233 |
-$26,039,432 |
2,801,636 |
-41% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| ENTX |
Entera Bio Ltd. |
Ordinary shares, par value NIS 0.0000769 per share |
2.6% |
$2,153,271 |
-$2,763,568 |
1,183,116 |
-56% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| CTMX |
CytomX Therapeutics, Inc. |
Common Stock, par value $0.00001 per share |
2.5% |
$12,978,754 |
-$12,811,193 |
4,068,575 |
-50% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| VNET |
VNET Group, Inc. |
Class A Ordinary Shares, par value $0.00001 per share |
2.4% |
$295,901,634 |
-$314,996,162 |
38,180,856 |
-52% |
Steven A. Cohen |
30 Jun 2025 |
| RPD |
Rapid7, Inc. |
Common Stock, par value $0.01 per share |
2.4% |
$34,974,135 |
|
1,502,971 |
|
Point72 Asset Management, L.P. |
31 Dec 2024 |
| OLMA |
Olema Pharmaceuticals, Inc. |
Common Stock, par value $0.0001 per share |
2.3% |
$4,909,701 |
|
1,543,931 |
|
Point72 Asset Management, L.P. |
31 Mar 2025 |
| ARRY |
Array Technologies, Inc. |
Common Stock, par value $0.001 per share |
2% |
$13,012,822 |
-$19,422,763 |
3,054,653 |
-60% |
Point72 Asset Management, L.P. |
31 Mar 2025 |
| DYN |
Dyne Therapeutics, Inc. |
Common Stock, par value $0.0001 per share |
1.5% |
$12,603,532 |
-$26,630,775 |
1,669,342 |
-68% |
Point72 Asset Management, L.P. |
31 Mar 2025 |
| LITE |
Lumentum Holdings Inc. |
Common Stock, par value $0.001 per share |
1.3% |
$110,518,907 |
-$408,208,441 |
895,470 |
-79% |
Point72 Asset Management, L.P. |
30 Jun 2025 |
| SPHR |
Sphere Entertainment Co. |
Class A Common Stock, par value $0.01 per share |
0.8% |
$13,881,584 |
-$81,500,570 |
223,464 |
-85% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| RGLS |
Regulus Therapeutics Inc. |
Common Stock, par value $0.001 per share |
0.3% |
$1,897,906 |
-$28,982,448 |
241,157 |
-94% |
Point72 Asset Management, L.P. |
30 Jun 2025 |
| ANNX |
Annexon, Inc. |
Common Stock, par value $0.001 per share |
0.1% |
$131,693 |
|
95,430 |
|
Point72 Asset Management, L.P. |
31 Mar 2025 |
| WHWK |
Whitehawk Therapeutics, Inc. |
Common Stock, par value $0.0001 per share |
0% |
$8,394 |
-$2,417,620 |
5,087 |
-100% |
Point72 Asset Management, L.P. |
31 Mar 2025 |
| KALA |
KALA BIO, Inc. |
Common Stock, par value $0.001 per share |
0% |
$407 |
-$742,054 |
257 |
-100% |
Point72 Asset Management, L.P. |
30 Sep 2025 |
| SYRS |
Syros Pharmaceuticals, Inc. |
Common Stock, par value $0.001 per share |
0% |
$9.92 |
|
496 |
|
Point72 Asset Management, L.P. |
31 Dec 2024 |
| IKT |
Inhibikase Therapeutics, Inc. |
Common Stock, par value $0.001 per share |
0% |
$0 |
|
0 |
|
Point72 Asset Management, L.P. |
31 Dec 2024 |
| JOYY |
JOYY Inc. |
Class A Common Shares, par value US$0.00001 per share |
0% |
$0 |
|
0 |
|
Point72 Asset Management, L.P. |
31 Mar 2025 |
| TSBX |
Turnstone Biologics Corp. |
Common Stock, par value $0.001 per share |
0% |
$0 |
|
0 |
|
Point72 Asset Management, L.P. |
30 Sep 2025 |
| SHLS |
Shoals Technologies Group, Inc. |
Class A Common Stock, par value $0.00001 per share |
0% |
$0 |
-$61,741,014 |
0 |
-100% |
Point72 Asset Management, L.P. |
30 Jun 2025 |
| CDMO |
Avid Bioservices, Inc. |
Common Stock, par value $0.001 per share |
0% |
$0 |
|
0 |
|
Point72 Asset Management, L.P. |
31 Dec 2024 |
| SGMT |
Sagimet Biosciences Inc. |
Series A Common Stock, par value $0.0001 per share |
0% |
$0 |
-$13,268,881 |
0 |
-100% |
Point72 Asset Management, L.P. |
30 Jun 2025 |